Flow-Sensitive Four-Dimensional Cine Magnetic Resonance Imaging for Offline Blood Flow Quantification in Multiple Vessels: A Validation Study
Flow-Sensitive Four-Dimensional Cine Magnetic Resonance Imaging for Offline Blood Flow Quantification in Multiple Vessels: A Validation Study
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DOI：
10.1002/jmri.22280
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发表时间：
2010-09-01
影响因子：
4.4
通讯作者：
Kuehne, Titus
中科院分区：
文献类型：
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作者：
Nordmeyer, Sarah;Riesenkampff, Eugenie;Kuehne, Titus
目的：进一步验证流量敏感四维速度编码电影磁共振成像（4D VEC MRI）对健康志愿者同时获得的静脉和动脉血流以及先天性心脏病患者血流异常的定量应用。材料和方法：比较7名志愿者在有或没有呼吸导航门控（门控/不门控）的情况下，通过标准二维（2D）和四维VEC MRI获得的胸动脉和静脉血管的脑卒中体积（SV）。此外，对瓣膜畸形和（或）瓣膜不全患者（n = 10）的主动脉或肺动脉干SV和反流分数（RF）进行二维和非四维VEC MRI方法的比较。结果：在志愿者和患者中。Bland-Altman测试显示2D之间具有良好的一致性。门控和非门控4D VEC MRI获得定量血流测量。2D和门控4D VEC MRI之间的偏差为
Purpose: To further validate the quantitative use of flow-sensitive four-dimensional velocity encoded cine magnetic resonance imaging (4D VEC MRI) for simultaneously acquired venous and arterial blood flow in healthy volunteers and for abnormal flow in patients with congenital heart disease.Materials and Methods: Stroke volumes (SV) obtained in arterial and venous thoracic vessels were compared between standard two-dimensional (2D), 4D VEC MRI with and without respiratory navigator gating (gated/nongated) in volunteers (n = 7). In addition, SV and regurgitation fractions (RF) measured in aorta or pulmonary trunk of patients with malformed and/or insufficient valves (n = 10) were compared between 2D and nongated 4D VEC MRI methods.Results: In volunteers and patients. Bland-Altman tests showed excellent agreement between 2D. gated, and nongated 4D VEC MRI obtained quantitative blood flow measurements. The bias between 2D and gated 4D VEC MRI was