A gutsy task: generating intestinal tissue from human pluripotent stem cells.

A gutsy task: generating intestinal tissue from human pluripotent stem cells.
复制标题

DOI:
10.1007/s10620-013-2620-2
复制
发表时间:
2013-05
影响因子:
3.1
通讯作者:
Spence JR
Spence JR
中科院分区:
医学3区
文献类型:
--
作者:
Finkbeiner SR;Spence JR

文献摘要

参考文献

被引文献

相似文献

近年来,对肠道发育、肠道干细胞稳态和分化的认识取得了许多重要进展。这些进展包括在三维基质中培养原代人类和小鼠肠上皮的新技术,以及从胚胎和诱导多能干细胞重新产生人类肠组织。这篇简短的评论将集中在人类多能干细胞定向分化成肠组织,突出这种组织的新用途,并比较和对比这个系统的原代肠上皮细胞培养。
Many significant advances in our understanding of intestine development, intestinal stem cell homeostasis and differentiation have been made in recent years. These advances include novel techniques to culture primary human and mouse intestinal epithelium in three-dimensional matrices, and de novo generation of human intestinal tissue from embryonic and induced pluripotent stem cells. This short review will focus on the directed differentiation of human pluripotent stem cells into intestinal tissue, highlight novel uses of this tissue, and compare and contrast this system to primary intestinal epithelial cultures.
DOI: 10.1128/mcb.00434-12
发表时间: 2012-09-01
影响因子: 5.3
作者:
de Lau, Wim;Kujala, Pekka;Clevers, Hans
通讯作者: Clevers, Hans
DOI: 10.1038/35082103
发表时间: 2001-06-21
期刊: NATURE
影响因子: 64.8
作者:
Brennan, J;Lu, CC;Robertson, EJ
通讯作者: Robertson, EJ
DOI: 10.1016/j.ydbio.2008.11.020
发表时间: 2009-02-15
影响因子: 2.7
作者:
Cervantes S;Yamaguchi TP;Hebrok M
通讯作者: Hebrok M
DOI: 10.1634/stemcells.22-5-675
发表时间: 2004-01-01
期刊: STEM CELLS
影响因子: 5.2
作者:
Baxter, MA;Wynn, RF;Bellantuono, I
通讯作者: Bellantuono, I
DOI: 10.1128/mcb.00124-06
发表时间: 2006-12-01
影响因子: 5.3
作者:
Bosse, Tjalling;Piaseckyj, Christina M.;Krasinski, Stephen D.
通讯作者: Krasinski, Stephen D.