BIRTH-WEIGHT AND NON-INSULIN-DEPENDENT DIABETES - THRIFTY GENOTYPE, THRIFTY PHENOTYPE, OR SURVIVING SMALL BABY GENOTYPE
BIRTH-WEIGHT AND NON-INSULIN-DEPENDENT DIABETES - THRIFTY GENOTYPE, THRIFTY PHENOTYPE, OR SURVIVING SMALL BABY GENOTYPE
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DOI：
10.1136/bmj.308.6934.942
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发表时间：
1994-04-09
影响因子：
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通讯作者：
BENNETT, PH
中科院分区：
文献类型：
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作者：
MCCANCE, DR;PETTITT, DJ;BENNETT, PH
研究-确定皮马印第安人糖尿病患病率与出生体重的关系。设计-对1940-72年出生的婴儿进行随访研究，这些婴儿在20-39岁时接受了葡萄糖耐量试验。设置-吉拉河印第安人社区，亚利桑那州。受试者-1179名美国印第安人。主要结果测量-非胰岛素依赖型糖尿病的患病率（摄入碳水化合物后2小时血糖浓度大于或等于11.1 mmol/l）。结果：出生体重最低和最高者患病率最高。出生体重的年龄调整患病率
Objective-To determine the prevalence of diabetes in relation to birth weight in Pima Indians.Design-Follow up study of infants born during 1940-72 who had undergone a glucose tolerance test at ages 20-39 years.Setting-Gila River Indian community, Arizona.Subjects-1179 American Indians.Main outcome measure-Prevalence of non-insulin dependent diabetes mellitus (plasma glucose concentration greater-than-or-equal-to 11.1 mmol/l two hours after ingestion of carbohydrate).Results-The prevalence was greatest in those with the lowest and highest birth weights. The age adjusted prevalences for birth weights