Prevalence of glaucoma in Thailand: a population based survey in Rom Klao District, Bangkok
Prevalence of glaucoma in Thailand: a population based survey in Rom Klao District, Bangkok
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DOI：
10.1136/bjo.87.9.1069
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发表时间：
2003-09-01
影响因子：
4.1
通讯作者：
Rojanapongpun, P
中科院分区：
文献类型：
--
作者：
Bourne, RRA;Sukudom, P;Rojanapongpun, P
目的：为了确定患病率，人口统计学，机制，青光眼的视觉发病率在城市Thailand people.Methods：790名年龄在50岁或以上的受试者从Rom Klao区，曼谷，泰国，列举了在人口为基础的横断面研究。每例受试者均接受以下检查：视力、视野检查、裂隙灯检查、压平眼压计、前房角镜检查和散瞳后视盘检查。主要观察指标包括视力（logMAR）、视野、眼内压（IOP）、前房角镜特征、垂直杯/盘比（VCDR）、青光眼类型的患病率。青光眼的诊断依据是视盘外观和视野缺损。在视盘不能检查的眼睛，青光眼被诊断时，视力为99.5百分位数或有证据表明以前的青光眼surgery.Results：701受试者进行了检查（响应率88.7%）。在具有“正常”阈上视野的眼睛中，平均IOP为13.3 mm Hg（第97.5百分位数= 20 mm Hg）。VCDR的97.5次和99.5次重复性分别为0.72和0.86。在门诊检查的701名受试者中，有27名患有青光眼（3.8%，95%CI：2.5 ~ 5.6），16例原发性开角型青光眼（POAG，患病率2.3%，95%CI：1.3 - 3.7），6例为原发性闭角型青光眼（PACG，患病率0.9%，95%CI：0.3至1.9），5例为继发性青光眼（SecG，患病率0.7%，95%CI：0.2至1.7）。在43例单侧盲受试者中，青光眼是5例受试者（12%）的病因。1例受试者因青光眼而双侧失明（患病率11%，95% CI：0.3 - 61.9）。28人（4%）根据视盘外观怀疑青光眼，6人仅根据视野。98名受试者（14%）的双眼有“可闭角”，其中22人有原发性闭角（PAC，患病率3.1%，95%CI：1.9 - 4.7）; 14人有周边前粘连，8人有高眼压（OHT）。青光眼是严重单侧视力丧失的第二大常见原因。
Aim: To determine prevalence, demography, mechanism, and visual morbidity of glaucoma in urban Thai people.Methods: 790 subjects aged 50 years or older from Rom Klao district, Bangkok, Thailand, were enumerated in a population based cross sectional study. Each subject underwent the following investigations: visual acuity, visual field testing, slit lamp examination, applanation tonometry, gonioscopy, and an optic disc examination after mydriasis. Main outcome measures included visual acuity (logMAR), visual fields, intraocular pressure (IOP), gonioscopic characteristics, vertical cup/disc ratio (VCDR), prevalence of types of glaucoma. Glaucoma was diagnosed on the basis of optic disc appearance and visual field defects. In eyes in which the optic disc could not be examined, glaucoma was diagnosed when visual acuity was 99.5th percentile or there was evidence of previous glaucoma surgery.Results: 701 subjects were examined (response rate 88.7%). In eyes with "normal" suprathreshold visual fields, the mean IOP was 13.3 mm Hg (97.5th percentile = 20 mm Hg). The 97.5th and 99.5th percentiles of VCDR were 0.72 and 0.86 respectively. Of the 701 subjects examined in the clinic, 27 had glaucoma (3.8%, 95% CI: 2.5 to 5.6), 16 had primary open angle glaucoma (POAG, prevalence 2.3%, 95% CI: 1.3 to 3.7), six were primary angle closure glaucoma (PACG, prevalence 0.9%, 95% CI: 0.3 to 1.9), and five were secondary glaucoma (SecG, prevalence 0.7%, 95% CI: 0.2 to 1.7). Among the 43 unilaterally blind subjects, glaucoma was the cause in five subjects (12%). One subject was bilaterally blind due to glaucoma (prevalence 11%, 95% CI: 0.3 to 61.9). 28 people (4%) were glaucoma suspects on the basis of optic disc appearance and six on the basis of visual fields only. 98 subjects (14%) had "occludable angles" in either eye, 22 of whom had primary angle closure (PAC, prevalence 3.1%, 95% CI: 1.9 to 4.7); 14 had peripheral anterior synechiae in either eye and eight had ocular hypertension (OHT).Conclusions: POAG accounted for 67% of all glaucoma, PACG 21%, and secondary glaucomas 12%. Glaucoma was the second most common cause of severe unilateral visual loss.