SPIN-GLASSES AND THE STATISTICAL-MECHANICS OF PROTEIN FOLDING

SPIN-GLASSES AND THE STATISTICAL-MECHANICS OF PROTEIN FOLDING
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DOI:
10.1073/pnas.84.21.7524
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发表时间:
1987-11-01
影响因子:
11.1
通讯作者:
WOLYNES, PG
WOLYNES, PG
中科院分区:
综合性期刊1区
文献类型:
--
作者:
BRYNGELSON, JD;WOLYNES, PG

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利用自旋玻璃理论研究了一个简单的蛋白质折叠模型。计算了该模型的相图,并简要报道了动力学计算结果。这些结果的关系,折叠实验,这些假设与以前的蛋白质折叠理论的关系,以及这些假设的蛋白质折叠预测方案的含义进行了讨论。
The theory of spin glasses was used to study a simple model of protein folding. The phase diagram of the model was calculated, and the results of dynamics calculations are briefly reported. The relation of these results to folding experiments, the relation of these hypotheses to previous protein folding theories, and the implication of these hypotheses for protein folding prediction schemes are discussed.