Importance of REP values when comparing the CALUX bioassay results with chemoanalyses results - Example with spiked vegetable oils

Importance of REP values when comparing the CALUX bioassay results with chemoanalyses results - Example with spiked vegetable oils
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DOI:
10.1016/j.talanta.2004.05.029
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发表时间:
2004-08-08
期刊:
影响因子:
6.1
通讯作者:
Goeyens, L
Goeyens, L
中科院分区:
化学1区
文献类型:
--
作者:
Carbonnelle, S;Van Loco, J;Goeyens, L

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观察到化学激活荧光素酶基因表达(CALUX)生物测定与化学分析结果之间的差异。本文表明,使用REP值而不是WHO TEF值计算TEQ值得到不同的结果。REP值确实会影响CALUX技术获得的结果。这些差异在二恶英类多氯联苯化合物(CALUX TEQ值低于WHO TEQ值)中比在二恶英类化合物(CALUX TEQ值高于WHO TEQ值)中更为显著。(C)2004 Elsevier B.V.保留所有权利。
Differences between chemical activated luciferase gene expression (CALUX) bioassay and chemoanalyses results are observed. This paper shows that calculations of the TEQ values using REP values instead of WHO TEF values give different results. The REP values do affect the results obtained by the CALUX technique. These differences are more marked for the dioxin like PCB compounds (CALUX TEQ values are lower than WHO TEQ values) than for the dioxin compounds (CALUX TEQ values are higher than WHO TEQ values).The CALUX results were compared with the concentrations of the congeners' spiked into the oil. (C) 2004 Elsevier B.V. All rights reserved.