Dietary patterns and A1C in Japanese men and women
Dietary patterns and A1C in Japanese men and women
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DOI：
10.2337/dc08-0297
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发表时间：
2008-08-01
期刊：
影响因子：
16.2
通讯作者：
Takayanagi, Ryoichi
中科院分区：
文献类型：
--
作者：
Nanri, Akiko;Mizoue, Tetsuya;Takayanagi, Ryoichi
目的：西方人群的饮食模式与2型糖尿病有关，但饮食在日本的作用尚不清楚。我们研究了日本成年人主要饮食模式与糖化血红蛋白测量的葡萄糖耐量状态之间的关系。研究设计和方法：受试者组由3243名男性和4667名女性组成，他们参加了日本福冈一项正在进行的生活方式相关疾病队列研究的基线调查。饮食模式是通过对49种食物的消费进行主成分分析得出的，并通过食物频率问卷确定。采用Logistic回归分析估计A1C升高的性别特异性比值比（ORs）（>= 5.5%），并对潜在的混杂变量进行校正。结果：以频繁摄入面包而不频繁摄入大米为特征的西化早餐模式与A1C浓度呈负相关（男性和女性的p趋势均为0.02）；男性和女性最高五分位数与最低五分位数的多变量调整后的or分别为0.60 （95% CI 0.43-0.84）和0.64（0.46-0.90）。仅男性的海产品饮食模式与A1C浓度呈正相关（p趋势= 0.01）。健康和高脂肪饮食模式与糖化血红蛋白无关。结论：经常摄入白米饭的饮食模式可能会恶化日本男性和女性的葡萄糖代谢，而咸味海鲜的饮食模式可能对男性有类似的影响。
OBJECTIVE - Dietary patterns in Western populations have been linked to type 2 diabetes, but the role of diet in Japanese remains unclear. We investigated the association between major dietary patterns and glucose tolerance status as measured by A1C in Japanese adults.RESEARCH DESIGN AND METHODS - The groups of subjects were comprised of 3,243 men and 4,667 women who participated in the baseline survey of an ongoing cohort study on lifestyle-related diseases in Fukuoka, Japan. Dietary patterns were derived by using principal-component analysis of the consumption of 49 food items, ascertained by a food-frequency questionnaire. Logistic regression analysis was used to estimate sex-specific odds ratios (ORs) of elevated A1C (>= 5.5%), with aqjustment for potential confounding variables.RESULTS - The Westernized breakfast pattern characterized by frequent intake of bread but infrequent intake of rice was inversely related to A1C concentrations (P-trend = 0.02 in both men and women); the multivariate-adjusted ORs for the highest versus lowest quintiles were 0.60 (95% CI 0.43-0.84) and 0.64 (0.46-0.90) for men and women, respectively. The seafood dietary pattern was Positively associated With A1C concentrations in men only (P-trend = 0.01). Neither the healthy nor high-fat dietary pattern was related to A1C.CONCLUSIONS - A dietary pattern featuring frequent intake of white rice may deteriorate glucose metabolism in Japanese men and women, and the salty seafood dietary pattern may have a similar effect in men.