CHANGES IN MORPHOLOGY AND PHYSIOLOGY OF OLFACTORY RECEPTOR CILIA DURING DEVELOPMENT
CHANGES IN MORPHOLOGY AND PHYSIOLOGY OF OLFACTORY RECEPTOR CILIA DURING DEVELOPMENT
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DOI：
10.1016/0306-4522(82)90232-9
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发表时间：
1982-01-01
期刊：
影响因子：
3.3
通讯作者：
BLANK, DL
中科院分区：
文献类型：
--
作者：
MAIR, RG;GESTELAND, RC;BLANK, DL
脊椎动物[蛙尖音]的纤毛嗅觉受体神经元在一生中不断翻转。这些神经元在不同的发育阶段具有不同类型的纤毛;新分化细胞上的纤毛短且能动;成熟细胞上的纤毛长且不动; Mg 2+和腺苷5“-三磷酸是纤毛运动所必需的;用气味刺激可以诱导同步运动，并且该过程由Ca 2+介导。受体神经元可能有两种可区分的发育状态：第一种，在生长的轴突与大脑建立突触连接之前，细胞带有运动的纤毛，通常是易激的;第二种，纤毛长而不动，细胞可以在气味之间区分。
Ciliated olfactory receptor neurons in vertebrates [Rana pipiens] turn over throughout life. These neurons bear different types of cilia at different developmental stages; cilia on newly differentiating cells are short and motile; cilia on mature cells are longer and immotile; Mg2+ and adenosine 5''-tri-phosphate are requisite for ciliary motion; stimulation with odorants can induce synchronous motion, and this process is mediated by Ca2+. Receptor neurons may have 2 distinguishable developmental states: in the first, before the growing axon establishes synaptic connection to the brain, the cells bear motile cilia and are generally irritable; the 2nd, the cilia are long and immotile, and the cells can be distinghished between odorants.