Discrimination of facial identity and of emotions in Alzheimer's disease
Discrimination of facial identity and of emotions in Alzheimer's disease
复制标题
DOI：
10.1016/s0022-510x(97)00222-0
复制
发表时间：
1998-02-05
影响因子：
4.4
通讯作者：
Boller, F
中科院分区：
文献类型：
--
作者：
Roudier, M;Marcie, P;Boller, F
目的：探讨阿尔茨海默病（AD）患者对人脸身份和情绪表达的加工过程。背景：面孔识别的机制可能与面孔表情识别的机制无关。面孔失认症患者通常保留了处理情绪面部表情的能力，偶尔，局灶性病变患者可能会识别人脸，但无法识别他们的面部表情。这种分离在AD患者群体中尚未明确显示。方法：对31例疑似AD患者和14名正常对照者进行面孔和情绪辨别任务。结果如下：AD患者在辨别面部身份和命名和指向命名的情绪方面显着受损，但在辨别面部表情的情绪方面与对照组相当。面部识别和情绪识别的缺陷，在整体上，与MMS和乌鸦分数。情绪的歧视是不相关的，这表明这种能力是基于认知过程不同于那些潜在的MMS和PM47。结论：这种分离意味着两个独立的系统，一个致力于辨别面部身份，另一个致力于辨别情绪。这与AD中认知缺陷的模块化组织是一致的，并且可以解释众所周知的经验，即即使在患有严重痴呆症的患者中，非语言交流也通常保持有效。(C)1998爱思唯尔科学爱尔兰有限公司
Objective: To investigate processing of human faces identity and of emotional expressions in patients with Alzheimer's Disease (AD). Background: Mechanisms responsible fbr discriminating facial identity may be dissociated from those involved in discriminating facial expressions. Patients with prosopagnosia often have preserved capacities for processing emotional facial expressions and occasionally, patients with focal lesions may recognize human faces without being able to recognize their facial expression. Such a dissociation has not been clearly shown in groups of AD patients. Methods: Thirty-one probable AD patients and 14 control subjects were administered tasks of discrimination of faces and of emotions. Results: AD patients were significantly impaired in discriminating facial identities and in naming and pointing to named emotions, but were comparable to controls in discriminating facial expressions of emotion. The deficits of facial discrimination and of identification of emotions were, on the whole, correlated with the MMS and Raven scores. Discrimination of emotions was not correlated to either test, suggesting that this ability is based on cognitive processes different from those underlying the MMS and the PM47. Conclusions: This dissociation implies two separate systems, one dedicated to discrimination of facial identities and the other to discrimination of emotions. This is compatible with the modular organization of cognitive deficits in AD and may explain the well known experience that nonverbal communication often remains effective even in patients with severe dementia. (C) 1998 Elsevier Science Ireland Ltd.