Secular blood pressure trends in normotensive persons: the Framingham Study.
Secular blood pressure trends in normotensive persons: the Framingham Study.
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血压正常者的长期血压趋势：弗雷明汉研究。
DOI：
10.1016/0002-8703(93)90129-w
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发表时间：
1993
影响因子：
4.8
通讯作者：
A. Dannenberg
中科院分区：
文献类型：
--
作者：
W. Kannel;R. Garrison;A. Dannenberg
由于抗高血压治疗的普及率大幅增加，高血压患病率的趋势很难评估。在过去的三十年里，弗雷明汉研究队列的 5209 名成员的平均血压水平有所下降，而血压升高的比例仅为三分之一。然而，如果那些接受治疗且血压正常的人被定义为高血压，那么除了血压升高的人之外，高血压的患病率也会增加。三十年来，高血压发病率没有一致的长期趋势，但研究队列中三分之二的人最终患上了高血压。为了确定未经治疗的血压水平是否随时间变化，我们对三十年来血压正常的受试者的平均血压趋势进行了检查。在每 10 年的时间间隔内，平均收缩压和舒张压仅下降 1 毫米汞柱 (p< 0.001)。因此，血压正常的人群的血压一直相当稳定。由于高血压的发病率非常高，且未来的高血压发生在正常血压分布的上端，因此迫切需要一级预防。锻炼、避免盐和酒精等预防措施，尤其是控制体重，值得高度重视。
Trends in hypertension prevalence are difficult to assess because of a massive increase in the prevalence of antihypertensive treatment. Over the past three decades mean blood pressure levels among the 5209 members of the Framingham Study cohort have declined, and elevated blood pressure is only one third as prevalent. However, if those receiving treatment who have normalized blood pressures are defined as hypertensive, in addition to those with elevated blood pressure, the prevalence of hypertension has increased. No consistent secular trend in theincidenceof hypertension was noted over three decades, but high blood pressure eventually developed in two thirds of the study cohort. To determine whether untreated blood pressure levels are changing over time, trends in mean blood pressure were examined in normotensive subjects over three decades. Only a 1 mm Hg decline in mean systolic and diastolic pressure over each 10-year interval was noted (p< 0.001). Thus blood pressure in the normotensive segment of the population has been quite stable. Because the incidence of hypertension is very high and future hypertension arises from the upper end of the normal blood pressure distribution, there is an urgent need for primary prevention. Preventive measures such as exercise, avoidance of salt and alcohol, and especially weight control deserve a high priority.
1973-1974 年至 1980-1981 年高血压检测和控制的改进。
DOI：
--
发表时间：
1983
期刊：
JAMA : the journal of the American Medical Association
影响因子：
--
作者：
Folsom,AR;Luepker,RV;Gillum,RF;Jacobs,DR;Prineas,RJ;Taylor,HL;Blackburn,H
通讯作者：
Blackburn,H