Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama Spine Study

Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama Spine Study
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DOI:
10.1016/j.joca.2012.06.018
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发表时间:
2012-10-01
影响因子:
7
通讯作者:
Yoshida, M.
Yoshida, M.
中科院分区:
医学2区
文献类型:
--
作者:
Ishimoto, Y.;Yoshimura, N.;Yoshida, M.

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目的:本研究的目的是调查症状性腰椎管狭窄症 (LSS) 的患病率,并利用磁共振成像 (MRI) 在基于人群的队列中阐明症状性腰椎管狭窄症 (LSS) 与身体表现之间的关联。 设计:这项横断面研究是日本骨关节炎/骨质疏松症抗残疾研究 (ROAD) 的一部分,共有 1,009 名受试者(335 名受试者)参与研究。 对 674 名女性(平均年龄 66.3 岁,年龄范围 21-97 岁)进行了分析。一位经验丰富的骨科医生获取了所有参与者的病史并进行了身体测试。有症状的 LSS 诊断标准要求同时存在症状和放射学 LSS 结果。所有参与者均获得了 6 米步行时间、椅子站立时间和单腿站立时间。结果:症状性 LSS 的患病率为 9.3%(95% 置信区间 [CI]:7.7-11.3),男性为 10.1%(CI:7.4-13.8),女性为 8.9%(CI:7.0-11.3)。随着年龄的增长,不同性别的患病率存在​​差异。男性LSS患病率随年龄大于70岁差异不大,但女性LSS患病率随年龄增加而升高。在身体表现测量中,最大步速 6 米步行时间与症状性 LSS 显着相关 (P = 0.03)。结论:在类似于日本普通人群的队列中,症状性 LSS 的患病率约为 10%。在评估与症状性 LSS 相关的身体机能下降方面,以最大速度行走 6 米的时间是比以平常速度行走更敏感的指标。 (C) 2012 年国际骨关节炎研究协会。由爱思唯尔有限公司出版。保留所有权利。
Objective: The purpose of this study was to investigate the prevalence of symptomatic lumbar spinal stenosis (LSS) and to clarify the association between symptomatic LSS and physical performance using magnetic resonance imaging (MRI) in a population-based cohort.Design: This cross-sectional study was performed as a part of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) in Japan and 1,009 subjects (335 men, 674 women, mean age 66.3 years, age range 21-97 years) were analyzed. An experienced orthopedic surgeon obtained the medical history and performed the physical testing for all participants. Symptomatic LSS diagnostic criteria required the presence of both symptoms and radiographic LSS findings. A 6-m walking time, chair standing time, and one-leg standing time were obtained from all participants.Results: The prevalence of symptomatic LSS was 9.3% (95% confidence interval [CI]: 7.7-11.3) overall, 10.1% (CI: 7.4-13.8) in men and 8.9% (Cl: 7.0-11.3) in women. There was a difference in the prevalence with increasing age by gender. The LSS prevalence showed little difference with age greater than 70 years for men, but the LSS prevalence for women was higher with increasing age. Among physical performance measures, 6-m walking time at a maximal pace was significantly associated with symptomatic LSS (P = 0.03).Conclusion: The prevalence of symptomatic LSS was approximately 10% in a cohort resembling the general Japanese population. A 6-m walking time at a maximal pace was a more sensitive index than walking at a usual pace in assessing decreased physical performance associated with symptomatic LSS. (C) 2012 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.