Alcohol intake and its relationship with bone mineral density, falls, and fracture risk in older men
Alcohol intake and its relationship with bone mineral density, falls, and fracture risk in older men
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DOI：
10.1111/j.1532-5415.2006.00912.x
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发表时间：
2006-11-01
影响因子：
6.3
通讯作者：
Cummings, Steven R.
中科院分区：
文献类型：
--
作者：
Cawthon, Peggy M.;Harrison, Stephanie L.;Cummings, Steven R.
研究酒精摄入量和问题饮酒史与骨密度（BMD）、福尔斯和骨折风险之间的关系。横断面和前瞻性队列研究。美国6个临床中心。5974名65岁及以上男性。基线时确定酒精摄入量和问题饮酒史。福尔斯随访时间为1年，骨折平均随访时间为3.65年。（35.5%）报告酒精摄入量有限（< 12杯/年）;在基线前一年，3，156例（52.8%）报告轻度摄入（< 14杯/周），697例（11.7%）报告中度至重度摄入（>= 14杯/周）。1001名男性（16.8%）曾经有过饮酒问题。在多变量模型中，随着酒精摄入量的增加，髋部和脊柱BMD也增加（趋势P
To examine the association between alcohol intake and problem drinking history and bone mineral density (BMD), falls and fracture risk.Cross-sectional and prospective cohort study.Six U.S. clinical centers.Five thousand nine hundred seventy-four men aged 65 and older.Alcohol intake and problem drinking histories were ascertained at baseline. Follow-up time was 1 year for falls and a mean of 3.65 years for fractures.Two thousand one hundred twenty-one participants (35.5%) reported limited alcohol intake (< 12 drinks/y); 3,156 (52.8%) reported light intake (< 14 drinks/wk), and 697 (11.7%) reported moderate to heavy intake (>= 14 drinks/wk) in the year before baseline. One thousand one men (16.8%) had ever had problem drinking. In multivariate models, as alcohol intake increased, so did hip and spine BMD (P for trend