The ‘BN2’ gene, a regulator for the onset of chromosome condensation
The ‘BN2’ gene, a regulator for the onset of chromosome condensation
复制标题
“BN2”基因，染色体浓缩开始的调节因子
作者：
T. Nishimoto
本文综述了染色质的凝聚-去凝聚循环。这种循环可以越来越详细地进行分析，因为可以获得表征良好的温度敏感细胞周期突变体，其中在非允许温度下对冷凝的控制是异常的。DNA转染和基因克隆技术使用一个这样的突变导致鉴定基因参与正常调节进入有丝分裂。
This review deals with the condensation–decondensation cycle of chromatin. This cycle can be analysed in increasing detail because of the availability of well‐characterized temperature‐sensitive cell‐cycle mutants in which the control for condensation is aberrant at the non‐permissive temperature. DNA transfection and gene cloning techniques using one such mutant have resulted in the identification of a gene involved in the normal regulation of entry into mitosis.
DOI：
10.1073/pnas.80.10.2926
发表时间：
1983-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
DAVIS, FM;TSAO, TY;RAO, PN
通讯作者：
RAO, PN