Biomedical HIV Protection Among Gay and Bisexual Men Who Use Crystal Methamphetamine
Biomedical HIV Protection Among Gay and Bisexual Men Who Use Crystal Methamphetamine
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DOI：
10.1007/s10461-019-02739-7
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发表时间：
2019-11-22
影响因子：
4.4
通讯作者：
Prestage, Garrett
中科院分区：
文献类型：
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作者：
Hammoud, Mohamed A.;Jin, Fengyi;Prestage, Garrett
在男同性恋和双性恋男性（GBM）中使用晶体甲基苯丙胺（晶体）与无安全套肛交（CLAIC）和HIV感染有关。暴露前预防（PrEP）和不可检测的病毒载量（UVL）是重要的生物医学HIV预防策略。我们调查晶体的使用和艾滋病毒的性风险行为的背景下，PrEP和紫外线之间的关系。2018年，1367名GBM提供了有关晶体使用和艾滋病毒预防策略的详细信息。二元逻辑回归用于估计晶体使用和行为之间的关联。最近的水晶使用与同性恋男性的更多社会参与以及拥有更多性伴侣独立相关。晶体的使用也与从事CLAIC的GBM中PrEP和UVL的使用独立相关。虽然使用晶体的GBM更有可能参与CLAIC，但他们也更有可能使用生物医学艾滋病毒预防来减轻艾滋病毒感染的风险。
Use of crystal methamphetamine (crystal) among gay and bisexual men (GBM) has been associated with condomless anal intercourse with casual partners (CLAIC) and HIV infection. Pre-exposure prophylaxis (PrEP) and undetectable viral load (UVL) are important biomedical HIV prevention strategies. We investigate the relationship between crystal use and HIV sexual risk behaviours in the context of PrEP and UVL. In 2018, 1367 GBM provided details about crystal use and HIV prevention strategies. Binary logistic regression was used to estimate associations between crystal use and behaviour. Recent crystal use was independently associated with greater social engagement with gay men and having more sexual partners. Crystal use was also independently associated with use of PrEP and UVL among GBM who engaged in CLAIC. Although GBM who used crystal were more likely to have engaged in CLAIC, they were also more likely to use biomedical HIV prevention which mitigates against the risks of HIV infection.