Dynamic nuclear polarization in liquids
Dynamic nuclear polarization in liquids
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DOI：
10.1039/9781849730877-00155
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Tuerke, M. -T.
中科院分区：
文献类型：
--
作者：
Bennati, M.;Tkach, I.;Tuerke, M. -T.
自磁共振早期以来，与顺磁中心耦合的原子核的动态核极化(DNP)被用来获得关于分子运动和电子-核自旋弛豫的信息。在过去的几年里，这项技术经历了复兴，因为人们认识到它提供了一种方法来克服溶液和固体核磁共振的灵敏度限制，这对研究大分子络合物特别重要。在本章中，我们总结了DNP在解决方案中的物理和仪器方面，并讨论了最近的实验设计，这些设计打开了在非常不同的领域应用的大门。
Dynamic nuclear polarization (DNP) of nuclei coupled to paramagnetic centers has been used since the early years of magnetic resonance to obtain information about molecular motion and electron-nuclear spin relaxation. In the past few years, this technique has experienced a renaissance as it was recognized that it provides a means to overcome the sensitivity limits in solution and solid state NMR which is particularly important for the studies of macromolecular complexes. In this chapter, we summarize the physical and instrumental aspects of DNP in solution and we discuss the most recent experimental designs that open up the door to applications in very different fields.