Alkene Chemoselectivity in Ruthenium-Catalyzed Z-Selective Olefin Metathesis
Alkene Chemoselectivity in Ruthenium-Catalyzed Z-Selective Olefin Metathesis
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DOI：
10.1002/anie.201302724
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发表时间：
2013-08-19
影响因子：
16.6
通讯作者：
Grubbs, Robert H.
中科院分区：
文献类型：
--
作者：
Cannon, Jeffrey S.;Grubbs, Robert H.
螯合钌催化剂已经实现了高化学选择性的烯烃复分解反应。在内部E烯烃的存在下，末端和内部Z烯烃选择性地反应。产物以良好的收率和高的立体选择性生成新的Z烯烃。没有观察到与内烯烃的复分解产物。对末端烯烃的化学选择性也观察到了空间位阻和电子失活烯烃。
Chelated ruthenium catalysts have achieved highly chemoselective olefin metathesis reactions. Terminal and internal Z olefins were selectively reacted in the presence of internal E olefins. Products were produced in good yield and high stereoselectivity for formation of a new Z olefin. No products of metathesis with the internal E olefin were observed. Chemoselectivity for terminal olefins was also observed over both sterically hindered and electronically deactivated alkenes.