In vivo study of microcirculation in canine myocardium using the IVIM method
In vivo study of microcirculation in canine myocardium using the IVIM method
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DOI：
10.1002/mrm.10568
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发表时间：
2003-09-01
影响因子：
3.3
通讯作者：
Wen, H
中科院分区：
文献类型：
--
作者：
Callot, V;Bennett, E;Wen, H
采用体素内非相干运动(IVIM)方法在闭胸犬体内进行左室壁微循环的测量。具体来说，它使我们能够测量平均微流速度(400+/-40微米/S)和血管体积分数(11.1%+/-2.2%)，并观察毛细血管定向的方向性。还测量了水沿和垂直于肌纤维的表观扩散系数(ADC)。注射腺苷后，VVF增加25%，平均微流速度增加7%，而ADC值无明显变化。死后ADC下降28.5%。2003年出版，Wiley-Liss，Inc.(Dagger)。
The intravoxel incoherent motion (IVIM) method was implemented in closed-chest dogs to obtain measurements on microcirculation in the left ventricular wall in vivo. Specifically, it enabled us to measure the mean microflow velocity (400 +/- 40 mum/s) and the vascular volume fraction (VVF) (11.1% +/- 2.2%), and observe the directional preference of capillary orientation. The apparent diffusion coefficients (ADCs) of water along and perpendicular to myofibers were also measured. With vasodilatation by adenosine infusion, a 25% increase in the VVF and a 7% increase in the mean microflow velocity were observed, while no change in the ADC was detected. A 28.5% decrease of the ADC was observed postmortem. Published 2003 Wiley-Liss, Inc.(dagger).