Comparison of the human immunodeficiency virus (HIV) type 1-specific immunoglobulin G capture enzyme-linked Immunosorbent assay and the avidity index method for identification of recent HIV infections

Comparison of the human immunodeficiency virus (HIV) type 1-specific immunoglobulin G capture enzyme-linked Immunosorbent assay and the avidity index method for identification of recent HIV infections
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DOI:
10.1128/jcm.01055-07
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发表时间:
2008-01-01
影响因子:
9.4
通讯作者:
Kuecherer, Claudia
Kuecherer, Claudia
中科院分区:
医学2区
文献类型:
--
作者:
Loschen, Stephan;Baetzing-Feigenbaum, Joerg;Kuecherer, Claudia

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比较人类免疫缺陷病毒(HIV)1型特异性免疫球蛋白G捕获酶联免疫吸附试验(Bed-CEIA)和亲和力指数法的敏感性和特异性,以确定最近的HIV感染,使用148例样本(81例患者),代表感染时间为0到222周。两种试验的结果相似(敏感性分别为80%和74%[P=0.53];特异性分别为86%和82%[P=0.67])。
The sensitivity and specificity of the human immunodeficiency virus (HIV) type 1-specific immunoglobulin G capture enzyme-linked immunosorbent assay (BED-CEIA) were compared with those of the avidity index method to identify recent HIV infection using a panel of 148 samples (81 patients) representing durations of infection ranging from 0 to 222 weeks. The results from the two tests were similar (sensitivity of 80% versus 74% [P=0.53]; specificity of 86% versus 82% [P=0.67]).