Variance components and their implications for statistical information in medical data.
Variance components and their implications for statistical information in medical data.
复制标题
方差分量及其对医疗数据中统计信息的影响。
DOI：
10.1002/sim.4780100411
复制
发表时间：
1991
影响因子：
2
通讯作者：
Wright,EA
中科院分区：
文献类型：
--
作者：
Orav,EJ;Louis,TA;Palmer,RH;Wright,EA
We discuss general issues concerning the design and analysis of medical experiments involving repeated measures or hierarchical groupings of subjects within larger study units. Depending on the types of questions being investigated, the correlations induced by clustering can have dramatic impact on the effective sample size. The unique aspects of such experiments must be accounted for during analysis and during interpretation of the results. We illustrate these issues by using a variance components model to investigate the role of leadership in medical practice.
