Changing epidemiology of calcific aortic valve disease: 30-year trends of incidence, prevalence, and deaths across 204 countries and territories.
Changing epidemiology of calcific aortic valve disease: 30-year trends of incidence, prevalence, and deaths across 204 countries and territories.
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钙化性主动脉瓣疾病流行病学的变化：204 个国家和地区发病率、患病率和死亡的 30 年趋势
DOI：
10.18632/aging.202942
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发表时间：
2021-05-11
期刊：
影响因子：
--
通讯作者：
Hua P
中科院分区：
文献类型：
--
作者：
Yi B;Zeng W;Lv L;Hua P
钙化性主动脉瓣疾病（CAVD）与发病率和死亡率增加相关。我们的目的是阐明 CAVD 30 年的全球流行病学。从 1990 年到 2019 年，全球 CAVD 发病率、患病率和死亡率分别增加了 3.51 倍、4.43 倍和 1.38 倍，即使在年龄标准化后也没有任何下降趋势。 2019年，斯洛文尼亚的CAVD发病率（62.21/10万人）和患病率（1,080.06/10万人）最高，而塞浦路斯的死亡ASR最高（8.20/10万人）。人口老龄化是发病率的一个重要因素。与女性相比，患有 CAVD 的男性较多，而且男性的疾病患病率高峰更早。高收缩压、高钠饮食和铅暴露是 CAVD 死亡的主要危险因素。估计的年度百分比变化是一种估计 ASR 变化的指标，与 2019 年所有 204 个国家和地区的 ASR 和社会人口指数 (SDI) 的发病率和患病率显着相关（所有 p<0.0001）。随着寿命的延长和危险因素的增加，CAVD 的总体负担很高，并且仍在上升，不同性别、年龄和 SDI 水平存在差异。我们的研究结果为主要目的是改善人类健康的组织、机构和资源敲响了警钟。
Calcific aortic valve disease (CAVD) is associated with increased morbidity and mortality. We aimed to elucidate the 30-year epidemiology of CAVD globally. Global CAVD incidence, prevalence, and deaths increased 3.51-, 4.43-, and 1.38-fold from 1990 to 2019, respectively, without any decreasing trends, even after age standardization. In 2019, Slovenia had the highest age-standardized rate (ASR) of CAVD incidence (62.21/100,000 persons) and prevalence (1,080.06/100,000) whereas Cyprus had the highest ASR of deaths (8.20/100,000). Population aging was an important contributor to incidence. Compared with women, more men had CAVD and men had earlier peaks in disease prevalence. High systolic blood pressure, diet high in sodium, and lead exposure were the main risk factors for deaths owing to CAVD. The estimated annual percentage change, a measure to estimate the variation of ASR, was significantly associated with the ASR and sociodemographic index (SDI) in 2019 for incidence and prevalence across all 204 countries and territories (all p<0.0001). With increased lifespan and risk factors, the overall burden of CAVD is high and remains on the rise, with differences by sex, age, and SDI level. Our findings serve to sound the alarm for organizations, institutions, and resources whose primary purpose is to improve human health.
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影响因子：
5.9
作者：
Komnenov, Dragana;Levanovich, Peter E.;Rossi, Noreen F.
通讯作者：
Rossi, Noreen F.
DOI：
10.1016/b978-0-12-816960-5.00003-3
发表时间：
2020-01-01
期刊：
METAL NANOPARTICLES FOR DRUG DELIVERY AND DIAGNOSTIC APPLICATIONS
影响因子：
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通讯作者：
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DOI：
10.15420/ecr.2015.10.2.108
发表时间：
2015
期刊：
European cardiology
影响因子：
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作者：
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通讯作者：
Alotti N
DOI：
10.1016/j.echo.2017.02.009
发表时间：
2017-04-01
影响因子：
6.5
作者：
Baumgartner, Helmut;Hung, Judy;Otto, Catherine M.
通讯作者：
Otto, Catherine M.
DOI：
10.15420/ecr.2020.15.1.po13
发表时间：
2020-02-01
期刊：
European cardiology
影响因子：
--
作者：
Cheung, Bmy;Tsoi, M F;Cheung, T T
通讯作者：
Cheung, T T