Chronic motor cortex stimulation for movement disorders: A promising perspective
Chronic motor cortex stimulation for movement disorders: A promising perspective
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慢性运动皮层刺激治疗运动障碍：一个有希望的前景
作者：
A. Franzini;P. Ferroli;I. Dones;C. Marras;G. Broggi
摘要对5例丘脑手性和意向性肌阵挛患者进行慢性运动皮质刺激。四极电极条在局部麻醉下硬膜外放置，通过mri图像引导的单个中央前钻孔放置在中央沟形态识别之后。术中使用刺激来诱导受累部位的肌肉收缩，以确认电极的正确放置。在全身麻醉下植入内部起搏器前有一周的试验期。4例患者疼痛明显减轻，丘脑手部肌张力障碍和强直明显减轻，有意性肌阵挛明显减少。电极植入和刺激无并发症和不良反应。
Abstract Five patients affected by thalamic hand and intentional myoclonus have been evaluated and selected for chronic motor cortex stimulation. A quadripolar electrode strip was placed epidurally under local anesthesia through an MR-image-guided single precentral burr hole placed following the morphologic recognition of the central sulcus. Intra-operative stimulation was used to induce muscle contraction at the affected site to confirm the correct placement of the electrode. A one-week trial period preceded the implant of an internal pace-maker under general anesthesia. A remarkable decrease in pain was reported by four patients together with the reduction of dystonia and rigidity in thalamic hand and marked decrease of intentional myoclonus. No complications or undesired side effects of electrode implant and stimulation were observed.