Role of delay discounting in predicting change in HBA1c for individuals with prediabetes
Role of delay discounting in predicting change in HBA1c for individuals with prediabetes
复制标题
DOI：
10.1007/s10865-019-00026-3
复制
发表时间：
2019-10-01
影响因子：
3.1
通讯作者：
Bickel, Warren K.
中科院分区：
文献类型：
--
作者：
Epstein, Leonard H.;Paluch, Rocco A.;Bickel, Warren K.
大多数患有前驱糖尿病的人会转变为2型糖尿病。众所周知，体重增加预示着患糖尿病的风险增加，但另一个原因可能是对眼前回报的关注和对未来的漠视。延迟折扣（DD：未来后果的贬值）与2型糖尿病患者的肥胖和血糖控制不良有关。本研究旨在评估糖尿病前期患者的DD变化是否与HbA1c变化相关，而不仅仅是BMI变化。分层回归显示BMI （p = 0.008）和$1000 DD任务（p = 0.04）的变化与HbA1c变化相关，超出了人口统计学特征，完整模型占方差的25.8%。BMI增加和未来折扣增加的患者HbA1c增加最大。DD是预防糖尿病前期发展为2型糖尿病的新靶点。
The majority of people with prediabetes transition to type 2 diabetes. Weight gain is a known predictor of increasing the risk of diabetes, but another reason may be a focus on immediate rewards and discounting of the future. Delay discounting (DD: devaluation of future consequences) is related to obesity and poor glycemic control in persons with type 2 diabetes. This study was designed to assess whether changes in DD are associated with HbA1c change beyond BMI change in individuals with prediabetes. Hierarchical regression showed changes in BMI (p = 0.008) and the $1000 DD task (p = 0.04) were associated with HbA1c change beyond demographic characteristics, with the full model accounting for 25.8% of the variance. Those with greater BMI increases and greater increases in discounting of the future showed the greatest increases in HbA1c. DD represents a novel target to prevent progression from prediabetes to type 2 diabetes.