A highly efficient enantioselective synthesis of 2-methyl chromans via four sequential palladium-catalyzed reactions

A highly efficient enantioselective synthesis of 2-methyl chromans via four sequential palladium-catalyzed reactions
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DOI:
10.1016/j.tetlet.2004.12.043
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发表时间:
2005-02-07
影响因子:
1.8
通讯作者:
Yasuda, N
Yasuda, N
中科院分区:
化学4区
文献类型:
--
作者:
Palucki, M;Yasuda, N

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在钯催化下,通过四步反应实现了取代2-甲基苯并二氢吡喃的对映选择性合成。对两种不同底物的关键钯催化芳醚环的区域选择性合成进行了研究,以更好地了解影响反应选择性的因素。(C)2004爱思唯尔有限公司保留所有权利。
An enantioselective synthesis of substituted 2-methyl chromans was accomplished in four steps using four sequential Pd-catalyzed reactions. A study of the key palladium-catalyzed regioselective aryl ether ring fort-nation of two different substrates was also carried out to better understand the factors which affect the selectivity of the reaction. (C) 2004 Elsevier Ltd. All rights reserved.