In vivo strain assessment of the abdominal aortic aneurysm
In vivo strain assessment of the abdominal aortic aneurysm
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DOI：
10.1016/j.jbiomech.2014.11.016
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发表时间：
2015-01-21
影响因子：
2.4
通讯作者：
Di Martino, Elena S.
中科院分区：
文献类型：
--
作者：
Satriano, Alessandro;Rivolo, Simone;Di Martino, Elena S.
目前用于告知腹主动脉瘤手术决策的唯一标准是最大直径（> 5.5 cm）和生长速度，尽管一些研究已经确定需要更具体的风险指标。可能影响破裂风险的患者特异性生物力学变量将是对理解破裂风险的科学的有价值的补充，并被证明是患者的救生益处。主动脉的局部变形性与壁的局部机械性质有关，并且可以提供关于壁组织弱化状态的指示。我们提出了一种基于三维图像的方法来计算体内主动脉壁应变图。该方法适用于在心动周期中的不同阶段提供顺序图像的各种成像模态。我们将该方法应用于一系列使用电影MRI成像的腹部动脉瘤，在心动周期的不同阶段获得应变图。这些标测图可用于评价动脉瘤在基线和不同随访时间的扩张性，并为临床医生提供额外的指标，以帮助决定特定患者的最佳行动方案。(C)2014爱思唯尔有限公司版权所有。
The only criteria currently used to inform surgical decision for abdominal aortic aneurysms are maximum diameter ( > 5.5 cm) and rate of growth, even though several studies have identified the need for more specific indicators of risk. Patient-specific biomechanical variables likely to affect rupture risk would be a valuable addition to the science of understanding rupture risk and prove to be a life saving benefit for patients. Local deformability of the aorta is related to the local mechanical properties of the wall and may provide indication on the state of weakening of the wall tissue. We propose a 3D image-based approach to compute aortic wall strain maps in vivo. The method is applicable to a variety of imaging modalities that provide sequential images at different phases in the cardiac cycle. We applied the method to a series of abdominal aneurysms imaged using cine-MRI obtaining strain maps at different phases in the cardiac cycle. These maps could be used to evaluate the distensibility of an aneurysm at baseline and at different follow-up times and provide an additional index to clinicians to facilitate decisions on the best course of action for a specific patient. (C) 2014 Elsevier Ltd. All rights reserved.