Microwave-assisted selenium dioxide oxidation of aryl methyl ketones to aryl glyoxals
Microwave-assisted selenium dioxide oxidation of aryl methyl ketones to aryl glyoxals
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DOI：
10.1016/j.tetlet.2011.05.130
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发表时间：
2011-08-03
影响因子：
1.8
通讯作者：
Davies-Coleman, Michael T.
中科院分区：
文献类型：
--
作者：
Young, Ryan M.;Davies-Coleman, Michael T.
本文报道了微波辅助二氧化硒氧化合成苯基乙二醛和一系列对位取代芳基乙二醛的改进方法。对于活化的芳基甲基酮底物，反应时间已从几个小时减少到3分钟，对于失活的底物，反应时间已从几个小时减少到18分钟，所有反应都提供定量转化为相应的芳基乙二醛。(C)2011爱思唯尔有限公司保留所有权利。
We report an improved procedure for the synthesis of phenyl glyoxal and a series of para-substituted aryl glyoxals by microwave-assisted selenium dioxide oxidation. The reaction time has been reduced from several hours to three minutes for activated aryl methyl ketone substrates and 18 min for deactivated substrates, with all reactions affording quantitative conversion into the corresponding aryl glyoxals. (C) 2011 Elsevier Ltd. All rights reserved.