NOSE, THROAT, AND FECAL FLORA OF BEAGLE DOGS HOUSED IN LOCKED OR OPEN ENVIRONMENTS
NOSE, THROAT, AND FECAL FLORA OF BEAGLE DOGS HOUSED IN LOCKED OR OPEN ENVIRONMENTS
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DOI：
10.1128/aem.34.2.207-221.1977
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发表时间：
1977-01-01
影响因子：
4.4
通讯作者：
YALE, CE
中科院分区：
文献类型：
--
作者：
BALISH, E;CLEVEN, D;YALE, CE
在 26 至 30 个月之间，对饲养在封闭环境（即限制在无菌式隔离器中并提供无菌食物、空气和水）或开放环境中的雄性比格犬的鼻子、喉咙和粪便的微生物菌群进行评估。进入研究。从比格犬的鼻子、喉咙和粪便中培养出 45 个属、170 种不同种类或类型的微生物。梭状芽胞杆菌、真细菌、棒状杆菌、拟杆菌、乳酸杆菌和厌氧革兰氏阳性球菌占菌群中大部分微生物多样性。一些兼性厌氧菌，特别是链球菌和乳酸杆菌（粪便中），其数量与数量最多的厌氧菌相当。封闭环境的限制导致菌群中微生物的多样性增加，但微生物总数并没有大幅增加。尽管封闭狗的菌群中细菌的多样性有所增加，但有些细菌似乎比其他区域更喜欢胃肠道的某些区域。在这些封闭的狗中观察到的细菌多样性增加可能会给其他哺乳动物（包括人类）带来一些传染病问题，这些哺乳动物可能会长期被限制在封闭的超洁净环境中。
The microbial flora of the nose, throat and feces of male beagle dogs housed in locked environment (i.e. confined to germfree-style isolators and supplied with sterile food, air and water) or an open environment were assessed between 26 and 30 mo. into the study. Forty-five genera and 170 different species or types of microorganisms were cultured from the nose, throat and feces of the beagles. Clostridia, eubacteria, corynebacteria, bacteroides, lactobacilli and anaerobic, gram-positive cocci accounted for most of the microbial diversity in the flora. Some of the facultative anaerobes, especially streptococci and lactobacilli (in feces), occurred in numbers that were comparable to the most numerous anaerobic species. Confinement to the locked environment resulted in an increased diversity of microorganisms in the flora, but the total microbial counts did not increase to any great extent. Even with the increased diversity of bacteria in the flora of confined dogs, some bacteria seemed to favor certain areas of the gastrointestinal tract over others. The increased diversity of bacteria observed in these confined dogs may pose some infectious disease problems for other mammals (including humans) that may be confined to a locked, ultraclean environment for a prolonged period of time.