FREQUENCY OF E. COLI K ANTIGENS IN URINARY-TRACT INFECTIONS IN CHILDREN
FREQUENCY OF E. COLI K ANTIGENS IN URINARY-TRACT INFECTIONS IN CHILDREN
复制标题
儿童尿路感染中大肠杆菌 K 抗原的频率
DOI：
10.1016/s0140-6736(77)92111-0
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发表时间：
1977
期刊：
影响因子：
--
通讯作者：
G. Lidin‐Janson
中科院分区：
文献类型：
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作者：
B. Kaijser;U. Jodal;J. B. Robbins;L. A. Hanson;G. Lidin‐Janson
研究人员对急性肾盂肾炎、急性膀胱炎和无症状菌尿患者尿液以及健康学童粪便中的大肠杆菌体细胞（O）和被膜（K）抗原进行了研究。分型抗血清16荚膜酸性多糖K抗原，和5（编号1，2，3，12，和13）占70%的菌株从急性肾盂肾炎患者。这五种K抗原在其他三个研究组中的发现程度较低。因此，只有少数K多糖与E.上尿路的大肠杆菌。这一发现类似于只有某些荚膜类型的肺炎球菌、脑膜炎球菌和嗜人流感球菌与侵袭性相关。对E.大肠杆菌与上尿路疾病可能允许更成功的控制与预防性免疫接种。
The somatic (O) and capsular (K) antigens ofEscherichiacoli from the urine of patients with acute pyelonephritis, acute cystitis, and asymptomatic bacteriuria, and in the fæces of healthy schoolchildren have been investigated. Typing antisera for sixteen capsular acidic polysaccharide K antigens were used, and five (numbers 1, 2, 3, 12, and 13) accounted for 70% of isolates from patients with acute pyelonephritis. These five K antigens were found to a lesser extent in the three other study groups. Thus, only a few K polysaccharides are associated with virulent properties ofE. colifor the upper urinary tract. This finding is similar to the association of only some capsular types of pneumococci, meningococci, andHœmophilus influenzœwith invasiveness. The identification of virulence markers forE. coliassociated with upper-urinary-tract disease may permit more successful control with reference to preventive immunisation.