Isolation and characterization of microsatellite DNA markers in the malaria vector Anopheles nili
Isolation and characterization of microsatellite DNA markers in the malaria vector Anopheles nili
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DOI：
10.1046/j.1471-8286.2003.00462.x
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发表时间：
2003-09-01
期刊：
影响因子：
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通讯作者：
Weill, M
中科院分区：
文献类型：
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作者：
Berthomieu, A;Kengne, P;Weill, M
尼里按蚊广泛分布于非洲热带地区，似乎是中非一些农村森林地区疟疾的主要传播媒介。本文报道了11个微卫星多态位点的分离。nili基因组，在来自西非的样品中显示出高的个体多样性（0.58-0.96）。两个基因座显示出显着偏离哈代-温伯格比例在所有样品中，这表明了大量的频率无效等位基因。其余9个基因座是在这个物种的进一步遗传研究的良好候选人。
The mosquito Anopheles nili is widespread across tropical Africa and appears to be the major vector of malaria in some rural forested areas of central Africa. Here we describe the isolation of 11 microsatellite polymorphic loci from the A. nili genome, displaying a high among-individual diversity (0.58-0.96) in samples from west Africa. Two loci displayed a significant departure from Hardy-Weinberg proportions across all samples, suggesting a substantial frequency of null alleles. The remaining nine loci are good candidates for further genetic studies in this species.