Speech impairment in a large sample of patients with Parkinson's disease
Speech impairment in a large sample of patients with Parkinson's disease
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DOI：
10.1155/1999/327643
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发表时间：
1998-01-01
影响因子：
2.8
通讯作者：
Gates, S
中科院分区：
文献类型：
--
作者：
Ho, AK;Iansek, R;Gates, S
本研究将200例帕金森病（PD）患者的言语障碍分为5个总体严重程度级别，并描述了每个级别的相应类型（语音，清晰度，流畅性）和程度（按5点量表评分）。从两分钟的会话语音样本，参数的声音，流畅性和清晰度进行了评估，由两个训练有素的评分员。语音被认为是主要的缺陷，最经常受到影响和损害的程度比其他功能在初始阶段。发音和流畅性缺陷表现较晚，发音障碍匹配语音障碍的频率和范围在“严重”阶段。在“深度”损伤的最后阶段，发音是最常见的受损功能，在最低水平的性能。这项研究说明了语音和发音言语运动控制缺陷的突出性，并与步态和笔迹骨骼控制中的运动组和运动组不稳定性缺陷进行了比较。
This study classified speech impairment in 200 patients with Parkinson's disease (PD) into five levels of overall severity and described the corresponding type (voice, articulation, fluency) and extent (rated on a five-point scale) of impairment for each level. From two-minute conversational speech samples, parameters of voice, fluency and articulation were assessed by two trained-raters. Voice was found to be the leading deficit, most frequently affected and impaired to a greater extent than other features in the initial stages. Articulatory and fluency deficits manifested later, articulatory impairment matching voice impairment in frequency and extent at the 'Severe' stage. At the final stage of 'Profound' impairment, articulation was the most frequently impaired feature at the lowest level of performance. This study illustrates the prominence of voice and articulatory speech motor control deficits, and draws parallels with deficits of motor set and motor set instability in skeletal controls of gait and handwriting.