Estimating the rate of evolution of the rate of molecular evolution
Estimating the rate of evolution of the rate of molecular evolution
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DOI：
10.1093/oxfordjournals.molbev.a025892
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发表时间：
1998-12-01
影响因子：
10.7
通讯作者：
Painter, IS
中科院分区：
文献类型：
--
作者：
Thorne, JL;Kishino, H;Painter, IS
提出了一个简单的分子演化速率的演化模型。与贝叶斯方法，该模型可以作为重要的进化事件的日期估计的基础，即使在没有假设的恒定速率之间的进化谱系。该方法可以与任何广泛使用的核苷酸取代或氨基酸置换模型结合使用。它是通过分析rbcL蛋白质序列的数据集来说明的。
A simple model for the evolution of the rate of molecular evolution is presented. With a Bayesian approach, this model can serve as the basis for estimating dates of important evolutionary events even in the absence of the assumption of constant rates among evolutionary lineages. The method can be used in conjunction with any of the widely used models for nucleotide substitution or amino acid replacement. It is illustrated by analyzing a data set of rbcL protein sequences.