Cognitive and motor function in adults with spina bifida myelomeningocele: a pilot study.

Cognitive and motor function in adults with spina bifida myelomeningocele: a pilot study.
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脊柱脊虫脊髓脑纤维膨出的成年人的认知和运动功能:一项初步研究。

DOI:
10.1007/s00381-020-04964-1
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发表时间:
2021-04
期刊:
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
影响因子:
--
通讯作者:
Lee P
Lee P
中科院分区:
其他
文献类型:
--
作者:
Jasien JM;Mikati MA;Kolarova M;Smith B;Thera S;Lee P

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确定使用一组测试的可行性和实用性,到目前为止,在典型的成人人群中评估神经认知功能,并确定这些功能在成人SBM患者的频谱。前瞻性研究,其中15名参与者(平均年龄= 28.7 ± 8.7岁,范围= 19-45岁)完成了先前标准化为一般人群的目标测试组合(n = 5-15/测试)。结果与正常数据进行比较。在以下测试中注意到与标准平均值的统计学显著差异:蒙特利尔认知评估(莫卡)、功能活动问卷(FAQ)和NIH Fine Motor(敏捷度和握力)测试。NIH脑脊液、结晶和认知综合评分以及计时和GO(TUG)的队列平均值与标准平均值无差异。队列成功完成了所有测试。虽然认知的许多方面是正常的,但评估视觉结构、计算、运动和流畅功能的测试确实显示出与人群平均值的差异。许多测试评估多个领域是必要的,并可用于未来的老龄化研究,以欣赏频谱的认知和运动能力的成年人与SBM。
Determine the feasibility and utility of using a battery of tests utilized, so far, to assess neurological-cognitive functions in the typical adult population and identify the spectrum of these functions in adult SBM patients. Prospective study in which 15 participants (mean age = 28.7 ± 8.7 years, range = 19–45 years) completed the targeted battery of tests (n = 5–15/test) previously standardized to the general population. Results were compared with normative data. Statistically significant differences with normative means were noted in the following tests: Montreal Cognitive Assessment (MoCA), Functional Activities Questionnaire (FAQ), and NIH Toolbox Fine Motor (Dexterity and Grip Strength) tests. Cohort means for NIH Toolbox Fluid, Crystallized, and Cognitive Composite Scores and Timed Up and GO (TUG) were not different from normative means. All tests were successfully completed by cohort. Whereas many aspects of cognition were normal, tests assessing visual-constructural, calculation, motor, and fluency functions did show differences from population means. Numerous tests assessing multiple domains are needed and can be used in future aging studies to appreciate the spectrum of cognitive and motor abilities in adults with SBM.
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