Association of markers of systemic inflammation, C reactive protein, serum amyloid A, and fibrinogen, with socioeconomic status
Association of markers of systemic inflammation, C reactive protein, serum amyloid A, and fibrinogen, with socioeconomic status
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DOI：
10.1136/jech.57.9.730
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发表时间：
2003-09-01
影响因子：
6.3
通讯作者：
Palosuo, T
中科院分区：
文献类型：
--
作者：
Jousilahti, P;Salomaa, V;Palosuo, T
研究目的：全身性炎症可能在心血管疾病的发生发展中起重要作用。研究还表明，社会经济地位预测心血管事件独立于既定的危险因素。本研究的目的是分析三种敏感的全身性炎症标志物：C反应蛋白（CRP），血清淀粉样蛋白A蛋白（SAA）和纤维蛋白原与社会经济状况的关系。设计：横断面研究。地点：芬兰东部和南部。参与者：1503名年龄在45至74岁之间的男性，他们在1997年参加了心血管危险因素调查。根据受教育程度和家庭收入，男性被分为三个社会经济群体。主要结果：CRP的平均浓度（趋势p
Study objective: Systemic inflammation may play an important part in the development of cardiovascular disease. It has also been shown that socioeconomic status predicts cardiovascular events independently of established risk factors. The aim of this study was to analyse the association of three sensitive markers of systemic inflammation: C reactive protein (CRP), serum amyloid A protein (SAA), and fibrinogen, with socioeconomic status. Design: Cross sectional study. Setting: Eastern and southern Finland. Participants: 1503 men aged 45 to 74 years who participated in a cardiovascular risk factor survey in 1997. Based on the levels of education and family income, the men were classified to three socioeconomic groups. Main results: Mean concentrations of CRP (p for the trend