VARIANT ANGINA OF PRINZMETAL WITH NORMAL CORONARY ARTERIOGRAMS - VARIANT OF VARIANT
VARIANT ANGINA OF PRINZMETAL WITH NORMAL CORONARY ARTERIOGRAMS - VARIANT OF VARIANT
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DOI：
10.1161/01.cir.47.3.476
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发表时间：
1973-01-01
期刊：
影响因子：
37.8
通讯作者：
BACOS, J
中科院分区：
文献类型：
--
作者：
CHENG, TO;BASHOUR, T;BACOS, J
变异型心绞痛通常被认为是由单一主要冠状动脉的明显局灶性阻塞引起的，这应该是冠状动脉-大隐静脉旁路移植术的理想病变。如果能够证明这种一致的关联，那么识别这种临床综合征将具有特别的诊断和治疗重要性。在我们的心导管实验室研究的5例变异型心绞痛患者中，4例冠状动脉造影正常。从这项研究中可以得出两个重要结论。首先，在存在和不存在疼痛的情况下都可以观察到相同的ECG变化，因此可能低估了变异型心绞痛的发生率和严重程度。第二，在通过冠状动脉造影对变异型心绞痛患者进行更大范围的研究之前，我们必须对所有具有临床综合征的患者都是隐静脉旁路手术的手术候选者持保留态度。
Variant angina of Prinzmetal has been generally presumed to be caused by a significant focal obstruction in a single major coronary artery which should be an ideal lesion for aortocoronary saphenous vein bypass graft. Recognition of this clinical syndrome would then be of particular diagnostic and therapeutic importance if such a consistent association can be demonstrated. Of five patients with variant angina studied in our cardiac catheterization laboratories, four had normal coronary arteriograms. Two important conclusions may be derived from this study. First, identical ECG changes may be observed both in the presence and absence of pain and thus the incidence and severity of the variant angina could be underestimated. Second, until a larger series of patients with variant angina is studied by coronary arteriography, one must exercise reservation in assuming that all patients with the clinical syndrome are operative candidates for saphenous vein bypass surgery.