Control of specific gene expression in higher organisms. Expression of mammalian genes may be controlled by repressors acting on the translation of messenger RNA.
Control of specific gene expression in higher organisms. Expression of mammalian genes may be controlled by repressors acting on the translation of messenger RNA.
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高等生物中特定基因表达的控制。
DOI：
10.1126/science.166.3912.1474
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发表时间：
1969
期刊：
影响因子：
56.9
通讯作者：
E. Thompson
中科院分区：
文献类型：
--
作者：
G. Tomkins;Gelehrter Td;D. Granner;D. Martin;Samuels Hh;E. Thompson
人们普遍认为，复杂后生动物有机体中大多数完整细胞的遗传信息与其他细胞的遗传信息是相同的。因此，在一个给定的生物体中，细胞表型的巨大多样性必然源于这样一个事实：每个细胞只表达其全部遗传潜能的有限数量，不同的细胞类型表达其基因组的不同部分。一个完整
It is generally acknowledged that the genetic information in most complete cells of a complex metazoan organism is identical with that of every other cell. Within a given organism the tre-mendous diversity of cell phenotypes must therefore derive from the fact that each cell expresses only a limited amount of its full genetic potential and that different cell types express different portions of their genome. A complete