Volumetric modulated arc radiotherapy for carcinomas of the oro-pharynx, hypo-pharynx and larynx: A treatment planning comparison with fixed field IMRT
Volumetric modulated arc radiotherapy for carcinomas of the oro-pharynx, hypo-pharynx and larynx: A treatment planning comparison with fixed field IMRT
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DOI：
10.1016/j.radonc.2008.12.008
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发表时间：
2009-07-01
影响因子：
5.7
通讯作者：
Cozzi, Luca
中科院分区：
文献类型：
--
作者：
Vanetti, Eugenio;Clivio, Alessandro;Cozzi, Luca
目的：进行一项计划研究，以评价体调弧形放射治疗头颈部肿瘤患者的疗效。方法和材料：收集29例口咽、下咽和喉部鳞状细胞癌患者的CT资料。优化了采用RapicArc技术的固定束调强、单(RA1)和双(RA2)调制弧光计划。原发灶剂量处方为66Gy2.2Gy一次，中危结节60Gy一次，低危结节54Gy一次。PTV的计划目标是最小剂量&>95%。和最大剂量
Purpose: A planning study was performed to evaluate the performance of volumetric modulated arc radiotherapy on head and neck cancer patients. Conventional fixed field IMRT was used as a benchmark.Methods and materials: CT datasets of 29 patients with squamous cell carcinoma of the oro-pharynx, hypo-pharynx and larynx were included. Plans for fixed beam IMRT, single (RA1) and double (RA2) modulated arcs with the RapicArc technique were optimised. Dose prescription was set to 66 Gy to the primary tumour (at 2.2 Gy/fraction), 60 Gy to intermediate-risk nodes and 54 Gy to low-risk nodal levels. The planning objectives for PTV were minimum dose >95%. and maximum dose