Contrast-Enhanced Endoscopic Ultrasonography in Pancreatic Diseases: A Preliminary Study
Contrast-Enhanced Endoscopic Ultrasonography in Pancreatic Diseases: A Preliminary Study
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增强内镜超声检查在胰腺疾病中的应用：初步研究
DOI：
10.1111/j.1572-0241.1998.179_b.x
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发表时间：
1998
影响因子：
9.8
通讯作者：
Y. Naitoh
中科院分区：
文献类型：
--
作者：
Y. Hirooka;H. Goto;A. Ito;S. Hayakawa;Yoshihiro Watanabe;Y. Ishiguro;S. Kojima;T. Hayakawa;Y. Naitoh
目的：探讨超声造影在胰腺疾病中的应用价值。方法：37例胰腺疾病患者，其中导管细胞癌11例，粘液性肿瘤10例，假性囊肿5例，胰岛细胞瘤4例，慢性胰腺炎4例，浆液性囊腺瘤3例。超声内窥镜检查结束后，右侧正中静脉以1ml/S的速度注入Albunex(0.22ml/kg)，观察10min。在每种疾病中，确定病变是否有强化。由于所有的导管细胞癌、胰岛细胞瘤、慢性胰腺炎和浆液性囊腺瘤患者，以及5例粘液性肿瘤和3例假性囊肿患者都进行了血管造影，比较了血管造影图像和超声造影的血管密度。结果：胰岛细胞瘤和浆液性囊腺瘤患者的病变均有强化，8例粘液性肿瘤患者和3例慢性胰腺炎患者的病变均有强化。而导管细胞癌和假性囊肿者则未见增强效果。对比超声内窥镜和血管造影图像，发现3例血管造影显示血管减少，但超声图像增强效果明显。结论：超声内窥镜平扫和增强图像的联合评价对胰腺疾病的诊断有一定价值。
Objective:The purpose of this study was to clarify the usefulness of contrast-enhanced endoscopic ultrasonography in pancreatic diseases.Methods:The subjects comprised 37 patients with pancreatic diseases: 11 with ductal cell carcinoma, 10 with mucin-producing tumor, five with pseudo-cyst, four with islet cell tumor, four with chronic pancreatitis, and three with serous cystadenoma. After endoscopic ultrasonography, Albunex (0.22 ml/kg) was injected intravenously at a rate of 1 ml/s into the right median vein, and observation was continued for 10 min. The presence or absence of enhancement of the lesion was determined in each disease. Because all the patients with ductal cell carcinoma, islet cell tumor, chronic pancreatitis, and serous cystadenoma, as well as five with mucin-producing tumor and three with pseudo-cyst, underwent angiography, vascularity was compared between angiographic images and those of contrast-enhanced ultrasonography.Results:Enhancement of the lesion was observed in all patients with islet cell tumor and serous cystadenoma, in eight with mucin-producing tumor, and in three with chronic pancreatitis. However, no enhancement effect was observed in the patients with ductal cell carcinoma and those with pseudo-cyst. Comparison between the images of contrast-enhanced endoscopic ultrasonography and angiographic images showed three patients in whom angiograms were hypovascular, but enhancement effect was observed on ultrasonographic images.Conclusion:The combined evaluation of plain and enhanced images of endoscopic ultrasonography may be useful for the diagnosis of pancreatic diseases.