Outcome of atrial fibrillation ablation in pulmonary hypertension: Is pulmonary hypertension a modifiable risk factor?
Outcome of atrial fibrillation ablation in pulmonary hypertension: Is pulmonary hypertension a modifiable risk factor?
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房颤消融治疗肺动脉高压的结果：肺动脉高压是可改变的危险因素吗？
DOI：
10.1016/j.ijcha.2019.100360
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Dobrev,Dobromir
中科院分区：
文献类型：
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作者：
Linz,Dominik;Dobrev,Dobromir
期刊主页：http：//www.期刊爱思唯尔。心脏和血管系统风险因素，如肥胖、高血压、睡眠呼吸暂停和代谢综合征，这些都与全身炎症、神经体液激活、氧化应激、低氧血症、交感神经兴奋和心房心肌病有关（图1）[12-14]。因此，对AF患者PH严重程度进行更详细的表征和评估可能有助于更好地识别有风险的患者。PH是否是一个可改变的风险因素，或者更确切地说，是房颤消融术后诱发急性肾损伤的基础疾病的标志物，需要进一步的前瞻性研究。
journal homepage: http://www. journals. elsevier. com/ijc-heart-and-vasculature risk factors such as obesity, hypertension, sleep apnea and metabolic syndrome, which are all associated with systemic inflammation, neurohumoral activation, oxidative stress, hypoxemia, sympathetic excitation and atrial cardiomyopathy (Fig. 1)[12–14]. Thus, a more detailed characterization and assessment of the severity of PH in AF patients may help to better identify patients at risk. Whether PH is a modifiable risk factor or rather a marker of underlying disease predisposing to acute kidney injury after AF ablation warrants further prospective study.