DECLINING LUNG-CANCER RATES AMONG YOUNG MEN AND WOMEN IN THE UNITED-STATES - A COHORT ANALYSIS
DECLINING LUNG-CANCER RATES AMONG YOUNG MEN AND WOMEN IN THE UNITED-STATES - A COHORT ANALYSIS
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DOI：
10.1093/jnci/81.20.1568
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发表时间：
1989-10-18
影响因子：
10.3
通讯作者：
FRAUMENI, JF
中科院分区：
文献类型：
--
作者：
DEVESA, SS;BLOT, WJ;FRAUMENI, JF
尽管美国肺癌的年龄调整死亡率总体上继续上升，但45岁以下的死亡率已经开始下降。在这份报告中，我们表明，白色男性的下降幅度最大，在20世纪70年代中期至80年代中期之间下降了29%，但黑人男性以及白色和黑人女性也出现了下降。队列分析显示，肺癌发病率在1925-1930年左右出生的男性和1935-1940年左右出生的女性中达到峰值，此后有所下降。如果这些趋势继续下去，男性肺癌总死亡率将在1990年代开始下降，女性肺癌总死亡率将在2000年后开始下降。
Although overall age-adjusted rates of mortality from lung cancer in the United States continue to rise, rates at ages below 45 years have begun to decline. In this report we show that the decrease is greatest among white men, with a 29% drop between the mid-1970s mid-1980s, but a decrease also occurred among black men and white and black women. Cohort analyses revealed that the rates of lung cancer peaked among men born around 1925-1930 and among women born around 1935-1940, and have declined thereafter. If these trends continue, overall lung cancer mortality rates will start to decline in the 1990s among men and after the year 2000 among women.