Fabrication of Calcite Foam by Inverse Ceramic Foam Method
Fabrication of Calcite Foam by Inverse Ceramic Foam Method
复制标题
反相陶瓷泡沫法制备方解石泡沫
DOI：
10.4028/www.scientific.net/kem.529-530.153
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Ishikawa Kunio
中科院分区：
文献类型：
--
作者：
Tra Nguyen Thanh;Michito Maruta;K. Tsuru;A. Valanezhad;S. Matsuya;Ishikawa Kunio
我们之前报道过通过陶瓷泡沫法可以制备具有互连多孔结构的方解石泡沫，并转化为碳酸盐磷灰石（CO3Ap）。在陶瓷泡沫法中，使用聚氨酯海绵作为模板。将聚氨酯海绵浸入陶瓷浆料中，聚氨酯泡沫的支柱上覆盖有陶瓷粉末。之后将其干燥并在高温下烧结。通过这种方法生产的方解石泡沫由三维 (3D) 互连多孔结构组成，有利于细胞渗透。然而，所有泡沫都有一个共同的局限性：固有地缺乏与高孔隙率相关的机械强度。因此，本研究对反相泡沫陶瓷法进行了研究；以聚氨酯泡沫为模板的多聚氨酯涂层方法。在这项研究中，通过反向复制提高了抗压强度，从而降低了孔隙率，同时保持了互连性。将可燃合成树脂涂层引入到聚氨酯泡沫支柱上，使三角形支柱变得更加圆润和厚实，从而在泡沫结构内产生大的圆形毛细血管，满足成骨细胞定植的要求。具体来说，将聚氨酯泡沫依次浸入两种单体中，然后离心除去泡沫内多余的液体。树脂固化后，在泡沫支柱上涂覆一层合成树脂。然后将氢氧化钙Ca(OH)2浆料渗透到树脂涂覆的聚氨酯泡沫中。通过在 O2-CO2 流中在 600°C 下烧制，聚氨酯模板被烧掉，Ca (OH)2 转化为方解石。制备了负复制方解石泡沫，并对其微观结构进行了表征，具有互连性和改进的机械强度。本研究获得的结果表明，该方法在不牺牲互连结构的情况下显着提高了方解石泡沫的机械强度，这意味着该方法获得的方解石泡沫可以作为3D互连多孔CO3Ap泡沫的前体。
We have previously reported that calcite foam that had interconnected porous structure could be prepared by ceramic foam method and it transformed to carbonate apatite (CO3Ap). In the ceramic foam method, polyurethane sponge was used as a template. The polyurethane sponge was immersed in the ceramics slurry, and the strut of the polyurethane foam was covered by ceramic powder. After that it was dried and sintered at high temperature. Calcite foams produced by this approach were comprised of a three-dimensional (3D) interconnected porous structure that facilitated cell penetration. However, all foams have a common limitation: the inherent lack of mechanical strength associated with high porosity. Therefore, in this study, an inverse ceramic foam method was studied; multi polyurethane coating method using polyurethane foam as a template. In this study, the compressive strength was improved by an inverse replication allowed for decreasing porosity while at the same time maintaining the interconnectivity. The burnable synthetic resin coating layer was introduced onto struts of polyurethane foam to make the triangular struts become more round and thick, consequently producing large round capillary within the foam structure fulfilling the requirement for osteoblast colonization. In particular, polyurethane foam was dipped orderly into two monomers, followed by centrifugation to remove excess liquids inside foam. After resin curing, a layer of synthetic resin was coated strut of foam. Calcium hydroxide Ca (OH)2 slurry was then infiltrated into resin coated-polyurethane foam. By firing at 600°C in O2-CO2 stream, polyurethane template was burnt off and Ca (OH)2 was converted into calcite. Negative replicated calcite foam was fabricated and characterized micro-structurally with interconnectivity and improved mechanical strength. The results obtained in this study suggested that this method dramatically improved the mechanical strength of the calcite foam without sacrificing the interconnected structure, and this means that the calcite foam obtained in this method could be precursors for the 3D interconnected porous CO3Ap foam.