Pharmacologic Therapies for Obesity

Pharmacologic Therapies for Obesity
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DOI:
10.1016/j.gtc.2010.01.001
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发表时间:
2010-03-01
影响因子:
3.7
通讯作者:
Kaplan, Lee M.
Kaplan, Lee M.
中科院分区:
医学3区
文献类型:
--
作者:
Kaplan, Lee M.

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本文探讨肥胖症药物治疗的转变。它回顾了美国食品和药物管理局(Food and Drug Administration)目前批准的选择,以及一些被批准用于治疗肥胖的其他适应症的药物。由于体重调节是复杂的,并且冗余系统可以防止感知到的饥饿,因此针对个体患者的最佳治疗可能需要不同的行为、营养、药物、内窥镜和手术治疗组合。
This article examines the transitions in pharmacological therapy for obesity. It reviews the current options approved by the Food and Drug Administration and several drugs approved for other indications that can be used to treat obesity as well. Because weight regulation is complex and redundant systems protect against perceived starvation, optimal treatment of obesity in individual patients will likely require different combinations of behavioral, nutritional, pharmacologic, endoscopic, and surgical therapies.