Poly(L-lactide) (PLLA)/multiwalled carbon nanotube (MWCNT) composite: characterization and biocompatibility evaluation.
Poly(L-lactide) (PLLA)/multiwalled carbon nanotube (MWCNT) composite: characterization and biocompatibility evaluation.
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DOI：
10.1021/jp061628k
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发表时间：
2006-06
期刊：
影响因子：
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通讯作者：
Donghui Zhang;Madhuvanthi A. Kandadai;J. Čech;S. Roth;S. Curran
中科院分区：
文献类型：
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作者：
Donghui Zhang;Madhuvanthi A. Kandadai;J. Čech;S. Roth;S. Curran
碳纳米管（CNTs）/聚合物复合材料的制备及其物理性能的表征一直是研究的热点。其中，包含CNT和生物相容性聚合物的复合材料由于其用于特定生物医学应用的潜力而受到特别关注。本文报道了多壁碳纳米管/聚L-乳酸复合材料的制备及其相应的光谱（拉曼）和显微（SEM，TEM）表征。该复合材料的电子传输，热性能和生物相容性也进行了研究。拉曼光谱分析表明，PLLA与MWCNT之间的相互作用主要是通过疏水的C-CH 3官能团进行的。复合材料的直流电导率随着MWCNT负载量的增加而增加。这种行为可以通过逾渗机制来描述，其中在约14重量% MWCNT负载下观察到逾渗阈值，最大末端电导率为0.1S × cm（-1）。对PLLA/MWCNT复合材料的DSC研究表明，复合材料中的MWCNT具有诱导结晶和增塑聚合物基体的作用。细胞培养试验的结果表明，复合材料中MWCNT的存在抑制了成纤维细胞的生长。
Much effort has been directed at the fabrication of carbon nanotubes (CNTs)/polymer composites and the characterization of their physical properties. Among them, composites comprising CNTs and the biocompatible polymers are of special interest due to their potential for specific biomedical applications. we report the preparation of the MWCNT/poly(L-lactide) composite and the corresponding spectroscopic (Raman) and the microscopic (SEM, TEM) characterization. The electronic transport, thermal properties, and biocompatibility of this composite have also been investigated. The Raman spectroscopic analysis suggests the interaction between PLLA and MWCNT occurs mainly through the hydrophobic C-CH3 functional groups. The DC conductivity of the composite increases as the MWCNT loading is increased. Such behavior can be described by a percolation mechanism in which a percolation threshold at about 14 wt % MWCNT loading is observed with the maximum end conductivity of 0.1 S x cm(-1). The DSC study of the PLLA/MWCNT composite reveals that the MWCNTs in the composite have the effect of inducing crystallization and plasticizing the polymer matrix. The results from the cell culture test suggest that the presence of MWCNT in the composite inhibits the growth of the fibroblast cells.