Positively charged bioactive Ti metal prepared by simple chemical and heat treatments
Positively charged bioactive Ti metal prepared by simple chemical and heat treatments
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通过简单的化学和热处理制备的带正电的生物活性钛金属
DOI：
10.1098/rsif.2010.0129.focus
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发表时间：
2010-10-06
影响因子：
3.9
通讯作者：
Nakamura, Takashi
中科院分区：
文献类型：
--
作者：
Kokubo, Tadashi;Pattanayak, Deepak K.;Nakamura, Takashi
钛金属在普通酸处理后进行简单的热处理，可得到生物活性较高的骨结合钛金属。这种骨结合特性归因于在人体环境中钛金属表面形成了磷灰石。钛金属表面磷灰石的形成既不是由其表面粗糙度引起的，也不是由其表面析出的金红石相引起的，而是由其表面带正电引起的。钛金属表面带正电荷是因为酸性基团被吸附在钛金属表面形成的氢化钛上，即使在随后的热处理将氢化钛转化为氧化钛后，表面仍然存在酸性基团。这些结果为制备生物活性材料提供了一种基于正电荷表面的新原理。
A highly bioactive bone-bonding Ti metal was obtained when Ti metal was simply heat-treated after a common acid treatment. This bone-bonding property was ascribed to the formation of apatite on the Ti metal in a body environment. The formation of apatite on the Ti metal was induced neither by its surface roughness nor by the rutile phase precipitated on its surface, but by its positively charged surface. The surface of the Ti metal was positively charged because acid groups were adsorbed on titanium hydride formed on the Ti metal by the acid treatment, and remained even after the titanium hydride was transformed into titanium oxide by the subsequent heat treatment. These results provide a new principle based on a positively charged surface for obtaining bioactive materials.