Heartening news for head muscle development

Heartening news for head muscle development
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DOI:
10.1016/j.tig.2007.05.002
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发表时间:
2007-08-01
期刊:
影响因子:
11.4
通讯作者:
Kelly, Robert G.
Kelly, Robert G.
中科院分区:
生物学1区
文献类型:
--
作者:
Grifone, Raphaeelle;Kelly, Robert G.

文献摘要

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在胚胎学起源、运动神经支配和肌肉发生的上游激活物方面,分支头面部肌肉不同于所有其他骨骼肌。最近的一系列研究揭示了颅面部骨骼肌祖细胞与一群形成心肌的细胞之间存在着惊人的并列和重叠的遗传程序。这些数据揭示了相邻祖细胞不同的成肌命运,为研究颅面肌发生提供了一个新的框架。
Branchiomeric craniofacial muscles differ from all other skeletal muscles with respect to embryological origin, motor innervation and upstream activators of myogenesis. A series of recent studies has revealed a striking juxtaposition and overlapping genetic program of craniofacial skeletal muscle progenitor cells with a population of cells giving rise to cardiac muscle. The divergent myogenic fates of adjacent progenitor cells revealed by these data provide a new framework for the study of craniofacial myogenesis.