The changing characteristics of COVID-19 presentations: A regional comparison of SARS-CoV-2 hospitalised patients during the first and second wave
The changing characteristics of COVID-19 presentations: A regional comparison of SARS-CoV-2 hospitalised patients during the first and second wave
复制标题
COVID-19 表现的变化特征：第一波和第二波期间 SARS-CoV-2 住院患者的区域比较
DOI：
10.1101/2021.02.07.21251297
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Atkin C
中科院分区：
文献类型：
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作者：
Atkin C
背景本研究评估了第1波和第2波期间COVID-19住院患者的人口统计学和结局，方法纳入2020年3月10日至2020年7月5日（第1波）和2020年9月1日至2020年11月16日（第2波）期间在伯明翰大学医院NHS基金会信托基金会住院的所有SARS-CoV-2拭子阳性患者（n=4856），随后为28 days.ResultsWave 2患者更年轻，更种族多样性，有较少的合并症和疾病的介绍是温和的介绍。匹配这些因素后，死亡率降低，但没有差异，在重症监护admission. ConclusionBefore新的SARS-CoV-2变种，住院治疗的COVID-19患者的结果有所改善，但有类似的重症监护需求。
BackgroundThis study assesses COVID-19 hospitalised patient demography and outcomes during wave 1 and wave 2, prior to new variants of the virus.MethodsAll patients with a positive SARS-CoV-2 swab between 10thMarch 2020 and 5thJuly 2020 (wave 1) and 1stSeptember 2020 and 16thNovember 2020 (wave 2) admitted to University Hospitals Birmingham NHS Foundation Trust were included (n=4856), followed for 28 days.ResultsWave 2 patients were younger, more ethnically diverse, had less co-morbidities and disease presentation was milder on presentation. After matching for these factors, mortality was reduced, but without differences in intensive care admissions.ConclusionPrior to new SARS-CoV-2 variants, outcomes for hospitalised patients with COVID-19 were improving but with similar intensive care needs.