Inter-individual variation of bolus properties in triggering swallowing during chewing in healthy humans
Inter-individual variation of bolus properties in triggering swallowing during chewing in healthy humans
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DOI：
10.1111/joor.13044
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发表时间：
2020-07-25
影响因子：
2.9
通讯作者：
Inoue, Makoto
中科院分区：
文献类型：
--
作者：
Maeda, Rumiko;Takei, Eri;Inoue, Makoto
即使在健康人群中，咀嚼行为也存在很大差异。本研究旨在阐明咀嚼时丸的流变特性在个体之间是如何不同的。我们还研究了个体之间的吞咽阈值是否一致，以及吞咽时丸剂性质的差异是否影响吞咽运动。方法29名健康志愿者每日摄入8 g蒸米饭。根据第一次吞咽前的咀嚼时间，参与者被要求咀嚼食物，然后在咀嚼时间的50%、100%和150%时将食物吐出来或吞下。在7名志愿者中，测量了最大咬合力。结果在整个记录过程中，药丸的硬度逐渐降低。尽管咀嚼时间差异很大，但无论个体咀嚼时间的差异如何，时间与硬度之间都存在显著的负相关关系。在100%时间点，丸剂的内聚性没有变化，随后有轻微但显著的增加。咀嚼时间与丸剂黏附性无显著相关性。吞咽相关的上、下肌电信号爆发与咀嚼持续时间和丸剂性质无关，咀嚼持续时间不影响吞咽功能。结论咀嚼过程中微丸的硬度、黏结性等特性仅与咀嚼时间有关，微丸特性的差异并不影响吞咽起始和运动。
Background There is a wide variation of chewing behaviours even in healthy humans. The present study was aimed to clarify how the rheological properties of the bolus during chewing are different among individuals. We also investigated whether the swallowing threshold was consistent among the individuals and whether the difference in the bolus properties at the swallowing affected swallowing movement. Methods Twenty-nine healthy volunteers were asked to ingest 8 g of steamed rice. Based on the chewing duration defined by the time until first swallow, participants were asked to chew the food and then either spit it out or swallow it at 50%, 100% and 150% of chewing duration. In seven volunteers, the maximum bite force was measured. Results The hardness of the bolus gradually decreased throughout recording. Although the chewing duration varied widely, there was a significant negative correlation between time and hardness, regardless of the difference in individual chewing duration. The cohesiveness of the bolus was unchanged at the 100% time point, followed by a slight but significant increase. There was no significant correlation between the chewing duration and adhesiveness of the bolus. Swallowing-related bursts of Supra and Infra EMGs were not related to the chewing duration or bolus properties, and chewing duration did not affect swallowing function. Conclusion The current results suggest that the bolus properties such as the hardness and cohesiveness during chewing are just dependent on the chewing duration and the difference in the bolus properties does not affect the swallowing initiation and movement.