Small for gestational age-cognitive performance from infancy to adulthood: an observational study

Small for gestational age-cognitive performance from infancy to adulthood: an observational study
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DOI:
10.1111/1471-0528.16341
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发表时间:
2020-07-03
影响因子:
5.8
通讯作者:
Wolke, D.
Wolke, D.
中科院分区:
医学1区
文献类型:
--
作者:
Eves, R.;Mendonca, M.;Wolke, D.

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目的探讨出生小胎龄(SGA)是否会影响婴儿期至成年期的认知能力,以及这是否取决于所使用的SGA参考值。此外,在考虑极早产/极低出生体重(VP/VLBW)、社会经济地位(SES)和亲子关系的影响下,确定SGA的影响。设计、环境和人群巴伐利亚纵向研究共414名参与者(足月出生者197名,副出生者217名)。方法采用新生儿或胎儿生长参考资料对胎龄小进行分类。在婴儿5个月前对SES和亲子关系进行评估。主要结果测量发育(DQ)和智力(IQ)测试在6种情况下评估认知表现,从5个月到26岁。结果胎儿参考文献将更多的婴儿分类为SGA (
Objective To determine whether cognitive performance from infancy to adulthood is affected by being born small for gestational age (SGA), and if this depends on the SGA reference used. Furthermore, to determine SGA's effect while considering the effects of very preterm/very low birthweight (VP/VLBW), socio-economic status (SES) and parent-infant relationship. Design, setting and population A total of 414 participants (197 term-born, 217 VP/VLBW) of the Bavarian Longitudinal Study. Methods Small for gestational age was classified using neonatal or fetal growth references. SES and the parent-infant relationship were assessed before the infant was 5 months old. Main outcome measures Developmental (DQ) and intelligence (IQ) tests assessed cognitive performance on six occasions, from 5 months to 26 years of age. Results The fetal reference classified more infants as SGA (