Tissue characterization of intracranial tumors by magnetization transfer and spin-lattice relaxation parameters in vivo
Tissue characterization of intracranial tumors by magnetization transfer and spin-lattice relaxation parameters in vivo
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DOI：
10.1002/jmri.1880060403
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发表时间：
1996-07-01
影响因子：
4.4
通讯作者：
Kormano, M
中科院分区：
文献类型：
--
作者：
Kurki, T;Lundbom, N;Kormano, M
在0.1 t的体内确定36个颅内肿瘤的T1s和磁化转移（MT）参数，以评估其在组织表征中的使用。肿瘤组之间的移动水松弛时间（T1（W））没有差异，而T1，明显的MT松弛时间（T1（a））和几种肿瘤类型之间的参数MT对比（MTC）显着差异， MT速率（R（WM））证明了最显着的差异：R（WM）值可以可靠地分开高级和低级神经胶质瘤。肿瘤的T1（W）通常在与正常灰质的范围内相同，而其他参数与正常大脑的参数不同，结果表明MT速率比颅内肿瘤表征的其他参数优于在神经胶质瘤的评分中也有用。
T1s and magnetization transfer (MT) parameters of 36 intracranial tumors were determined in vivo at 0.1 T to assess their use in tissue characterization. The mobile water relaxation times (T1(w)) did not differ between tumor groups, whereas the T1s, the apparent MT relaxation times (T1(a)), and the parameters MT contrast (MTC) differed significantly between several tumor types, The MT rates (R(wm)) demonstrated the most significant differences: R(wm) values could reliably separate high grade and low grade gliomas. T1(w)s of the tumors were commonly in the same range as that of normal gray matter, whereas other parameters differed from those of normal brain, The results indicate that MT rates are superior to other parameters in the characterization of intracranial tumors and may be also useful clinically in the grading of gliomas.