Knee extensor strength is associated with Mini-Mental State Examination scores in elderly men
Knee extensor strength is associated with Mini-Mental State Examination scores in elderly men
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DOI：
10.1007/s00421-011-2176-9
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发表时间：
2012-05-01
影响因子：
3
通讯作者：
Mori, Shiro
中科院分区：
文献类型：
--
作者：
Nakamoto, Hiroki;Yoshitake, Yasuhide;Mori, Shiro
本研究调查了非残疾老年男性的膝伸肌力量是否与整体认知功能相关，通过简易精神状态检查（MMSE）进行评估。在 39 名 61-79 岁的非残疾男性中测定了最大自愿膝关节伸展、跖屈和肘关节屈曲期间的等长扭矩以及 MMSE 评分，并用于检查测量变量之间关联的横断面分析。此外，其中 27 名受试者参加了为期 3 个月的每周 6 天的基于体重的练习（坐在椅子上和从椅子上站起来、髋关节伸展和屈曲、小腿抬高、侧腿抬高以及躯干屈曲和伸展）组成的训练计划。干预后确定等长扭矩和 MMSE 评分。干预前的数据中，只有膝关节伸展扭矩（KET）和KET相对体重（KET/BM）与MMSE评分显着相关：KET r = 0.579（P < 0.0001），KET/BM r = 0.520（P < 0.001）。干预后，KET和KET/BM显着升高，但MMSE评分没有显着升高。然而，MMSE评分的绝对变化与KET（r = 0.381，P < 0.05）和KET/BM（r = 0.422，P < 0.05）的绝对变化显着相关。这些发现表明，膝关节伸肌的力量能力与非残疾老年男性的整体认知功能相关，并为老年人的阻力训练计划中应包括加强膝关节伸肌的锻炼这一一般概念提供了新的视角。
The present study examined whether the strength capability of knee extensor muscles is associated with global cognitive function, assessed by Mini-Mental State Examination (MMSE), in non-disabled elderly men. Isometric torques during maximal voluntary knee extension, plantar flexion, and elbow flexion and MMSE scores were determined in 39 non-disabled men aged 61-79 years and used for the cross-sectional analysis examining the associations among the measured variables. Moreover, 27 of the subjects participated in a training program consisted of body mass-based exercises (sitting down onto and standing up from a chair, hip joint extension and flexion, calf raises, side leg raises, and trunk flexion and extension) 6 days a week for 3 months. Isometric torques and MMSE scores were determined after the intervention. Among the data before intervention, only knee extension torque (KET) and KET relative to body mass (KET/BM) significantly correlated to the MMSE scores: r = 0.579 (P < 0.0001) for KET and r = 0.520 (P < 0.001) for KET/BM. After the intervention, KET and KET/BM increased significantly, but MMSE score did not. However, the absolute change in MMSE scores was significantly associated with that in KET (r = 0.381, P < 0.05) and KET/BM (r = 0.422, P < 0.05). These findings indicate that the strength capability of knee extensors is associated with global cognitive function in non-disabled elderly men, and provide a new perspective to a general concept that exercises strengthening knee extensor muscles should be included in resistance training programs for elderly individuals.