Bacteriophages and Bacterial Plant Diseases.
Bacteriophages and Bacterial Plant Diseases.
复制标题
噬菌体和细菌植物疾病。
DOI：
10.3389/fmicb.2017.00034
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发表时间：
2017
影响因子：
5.2
通讯作者：
Coffey A
中科院分区：
文献类型：
--
作者：
Buttimer C;McAuliffe O;Ross RP;Hill C;O'Mahony J;Coffey A
需要减少因疾病造成的作物产量损失，以满足与人口增长相关的全球粮食需求。开发新的环境友好的控制策略以对抗细菌性作物病害是公认的需要。目前使用传统化学品或抗生素的控制措施正在失去效力，因为细菌会自然产生对这些药剂的抗药性。此外，人们日益认识到，使用这些材料对环境有害。噬菌体是细菌的病毒，近年来作为控制细菌疾病的现实环境友好手段受到越来越多的研究兴趣。它们的使用为许多破坏性的细菌性作物疾病提供了一种可行的控制措施，一些基于噬菌体的产品已经在市场上销售。噬菌体生物防治具有优于化学防治的优势，因为定制的噬菌体鸡尾酒可以适应于靶向特定的致病细菌。与化学控制措施不同，噬菌体混合物可以很容易地适应可能随着时间的推移而发展的细菌抗性。在这篇综述中，我们将研究粮食作物中基于噬菌体的疾病生物防治的进展和挑战。
Losses in crop yields due to disease need to be reduced in order to meet increasing global food demands associated with growth in the human population. There is a well-recognized need to develop new environmentally friendly control strategies to combat bacterial crop disease. Current control measures involving the use of traditional chemicals or antibiotics are losing their efficacy due to the natural development of bacterial resistance to these agents. In addition, there is an increasing awareness that their use is environmentally unfriendly. Bacteriophages, the viruses of bacteria, have received increased research interest in recent years as a realistic environmentally friendly means of controlling bacterial diseases. Their use presents a viable control measure for a number of destructive bacterial crop diseases, with some phage-based products already becoming available on the market. Phage biocontrol possesses advantages over chemical controls in that tailor-made phage cocktails can be adapted to target specific disease-causing bacteria. Unlike chemical control measures, phage mixtures can be easily adapted for bacterial resistance which may develop over time. In this review, we will examine the progress and challenges for phage-based disease biocontrol in food crops.