Clinical Considerations for Patients Experiencing Acute Kidney Injury Following Percutaneous Nephrolithotomy.
Clinical Considerations for Patients Experiencing Acute Kidney Injury Following Percutaneous Nephrolithotomy.
复制标题
DOI：
10.3390/biomedicines11061712
复制
发表时间：
2023-06-14
期刊：
影响因子：
4.7
通讯作者：
中科院分区：
文献类型：
--
作者：
急性肾损伤（阿基）是接受肾结石手术的泌尿外科患者的常见术后结局。本研究的目的是确定术后阿基的患病率及其严重程度，识别风险因素，并了解肾结石患者接受经皮肾镜取石术（PCNL）后阿基的结果。回顾性分析了2012年至2019年期间在一家三级医疗机构接受PCNL的患者队列。在417例（n = 326例患者）就诊中，24.9%（n = 104例）发生阿基。大约四分之一的阿基患者（n = 18）进展为2期或更高阿基。高血压、外周血管疾病、慢性肾脏疾病和慢性贫血是PCNL术后阿基的重要危险因素。皮质类固醇和抗真菌药与阿基的几率增加相关。阿基患者的心血管、神经系统并发症、败血症和重症监护室（ICU）长期住院百分比较高。阿基组的住院和ICU住院时间更长。鉴于PCNL术后阿基的文献有限，以及阿基可能对临床结局造成的损害，继续研究该主题以更好地了解如何优化患者护理以解决患者和手术特定风险因素非常重要。
Acute kidney injury (AKI) is a common postoperative outcome in urology patients undergoing surgery for nephrolithiasis. The objective of this study was to determine the prevalence of postoperative AKI and its degrees of severity, identify risk factors, and understand the resultant outcomes of AKI in patients with nephrolithiasis undergoing percutaneous nephrolithotomy (PCNL). A cohort of patients admitted between 2012 and 2019 to a single tertiary-care institution who had undergone PCNL was retrospectively analyzed. Among 417 (n = 326 patients) encounters, 24.9% (n = 104) had AKI. Approximately one-quarter of AKI patients (n = 18) progressed to Stage 2 or higher AKI. Hypertension, peripheral vascular disease, chronic kidney disease, and chronic anemia were significant risk factors of post-PCNL AKI. Corticosteroids and antifungals were associated with increased odds of AKI. Cardiovascular, neurologic complications, sepsis, and prolonged intensive care unit (ICU) stay percentages were higher in AKI patients. Hospital and ICU length of stay was greater in the AKI group. Provided the limited literature regarding postoperative AKI following PCNL, and the detriment that AKI can have on clinical outcomes, it is important to continue studying this topic to better understand how to optimize patient care to address patient- and procedure-specific risk factors.
登录
查看更多内容
影响因子：
3.4
作者：
Kamphuis, Guido M.;Baard, Joyce;de la Rosette, Jean J. M. C. H.
通讯作者：
de la Rosette, Jean J. M. C. H.
影响因子：
--
作者：
Amin, Amit P.;Salisbury, Adam C.;Kosiborod, Mikhail
通讯作者：
Kosiborod, Mikhail
影响因子：
3.7
作者：
Adhikari, Lasith;Ozrazgat-Baslanti, Tezcan;Bihorac, Azra
通讯作者：
Bihorac, Azra
影响因子：
3
作者：
Elixhauser, A;Steiner, C;Coffey, RN
通讯作者：
Coffey, RN
DOI：
10.1016/j.jss.2020.05.007
发表时间：
2020-10
期刊：
The Journal of surgical research
影响因子：
--
作者：
Datta S;Loftus TJ;Ruppert MM;Giordano C;Upchurch GR Jr;Rashidi P;Ozrazgat-Baslanti T;Bihorac A
通讯作者：
Bihorac A